Columbia University Medical Center (CUMC) (Divisions)

Divisions

Columbia University Medical Center (CUMC)

Automated MRI-based breast cancer segmentation

CU26095

AI-driven, scalable MRI segmentation for breast cancer (DCIS); automates lesion delineation, boosting speed, consistency, and research utility.

Tags

Biomarker

Breast cancer

Breast cancer screening

Inventors

Despina Kontos

Kalina Slavkova

Manager

Joan Martinez

Departments

Radiology

Divisions

Columbia University Medical Center (CUMC)

Release Date

2026-02-20

Chimeric CRISPR-associated transposon system for RNA-mediated DNA integration

CU24119

Chimeric CAST enables efficient, RNA-guided DNA insertion without breaks, combining components for larger cargo in cells.

Tags

Coevolution

DNA repair

Enzyme

Inventors

George Davis Lampe

Samuel H. Sternberg

Manager

Cynthia Lang

Departments

Biochemistry & Molecular Biophysics

Divisions

Columbia University Medical Center (CUMC)

Release Date

2026-01-09

Collections

Genomics & Multi-Omics

Small molecule activators for preventing vision loss in Best vitelliform macular dystrophy

CU25176

Small molecule activators restore Best1 function to slow BVMD vision loss; targeted, potentially non-invasive retinal therapy.

Tags

4-Aminobenzoic acid

Drug development

Gene therapy

Inventors

Bingchen Yu

Tingting Yang

Yu Zhang

Manager

Joan Martinez

Departments

Chemistry

Ophthalmology

Divisions

Columbia University Medical Center (CUMC)

Release Date

2025-05-01

Collections

Ophthalmology

Microfluidic platform for large-scale single-cell sequencing and imaging

CU16248

Scalable, low-cost microfluidic platform linking live-cell imaging with single-cell RNA sequencing via optical barcodes.

Tags

Brain mapping

Cell culture

Drug discovery

Inventors

Jinzhou Yuan

Peter A. Sims

Sayantan Bose

Manager

Cynthia Lang

Departments

Biochemistry & Molecular Biophysics

Systems Biology

Divisions

Columbia University Medical Center (CUMC)

Release Date

2025-01-02

Collections

Genomics & Multi-Omics

Paramyxovirus fusion complex structure for antiviral and vaccine design

CU23202

A conserved paramyxovirus fusion complex structure enables targeted antivirals and vaccine design, stabilizing pre-fusion entry protein.

Tags

Antigen

Antiviral drug

Fusion protein

Inventors

Anne Moscona

Matteo Porotto

Tara Marcink

Manager

Kristin Neuman

Departments

Pediatrics

Divisions

Columbia University Medical Center (CUMC)

Release Date

2024-02-21

Therapeutic antibodies against amyloid aggregates

CU23354

Antibody platform targets TMEM106B amyloid aggregates for diagnosis, therapeutics, and research across neurodegenerative diseases.

Tags

Amyloid beta

Antibody

Biomarker

Inventors

Anthony William Paul Fitzpatrick

Carolyn Lee

Junqiang Ye Ph.D.

Manager

Kristin Neuman

Departments

Biochemistry

Biochemistry & Molecular Biophysics

Divisions

Columbia University Medical Center (CUMC)

Release Date

2026-02-26

tomoLIBRA: Deep learning software for automated volumetric breast density estimation

CU26015

AI-based tomoLIBRA estimates volumetric breast density from standard 3D DBT images, enabling scalable, retrospective risk assessment without raw data.

Tags

Breast cancer

Breast cancer screening

Case–control study

Inventors

Aimilia Gastounioti

Ari Brooks

Celine Vachon

Manager

Joan Martinez

Departments

Biomedical Engineering

Radiology

Divisions

Columbia University Medical Center (CUMC)

Fu Foundation School of Engineering and Applied Science (SEAS)

School of Medicine

Release Date

2026-02-20

Digital addiction monitoring and early mental health intervention platform

CU26164

Passive, trajectory-based digital addiction monitoring with adaptive mental-health interventions to preempt crises and escalate care.

Tags

Cohort study

Major depressive disorder

Mental health

Inventors

J. John Mann

Yunyu Xiao

Manager

Jerry Kokoshka

Departments

Psychiatry

Divisions

Columbia University Medical Center (CUMC)

Release Date

2026-02-17

Encryption method for secure storage and analysis of patient data on the cloud

CU24094

A cloud-friendly, privacy-preserving genomic analysis method using homomorphic encryption to enable multi-user queries on encrypted patient data.

Tags

Ciphertext

Cloud computing

Data management

Inventors

Gamze Gursoy

Jacob Blindenbach

Jiayi Kang

Manager

Joan Martinez

Departments

Biomedical Informatics

Computer Science

Divisions

Columbia University Medical Center (CUMC)

Fu Foundation School of Engineering and Applied Science (SEAS)

Release Date

2026-02-03

WDFY3 variant mouse models for neurodegenerative studies

CU26145

A clinically relevant WDFY3 knock-in mouse model to study autophagy’s role in neurodegenerative diseases and therapies.

Tags

Autophagy

Neurodegenerative disease

Neuron

Inventors

Ai Yamamoto

Manager

Kristin Neuman

Departments

Physiology and Cellular Biophysics

Divisions

Columbia University Medical Center (CUMC)

Release Date

2026-01-08

Artificial intelligence tool for rapid, automated electronic health record review

CU26003

AI-powered OphthoACR automates rapid, accurate ophthalmology EHR data extraction from unstructured notes and imaging.

Tags

Abstraction (computer science)

Artificial intelligence

Cohort study

Inventors

Karen Chen

Leejee Han Suh

Vlad Diaconita

Manager

Kristin Neuman

Departments

Ophthalmology

Physicians & Surgeons

Divisions

Columbia University Medical Center (CUMC)

Release Date

2025-10-23

Machine learning tool for diagnosis of cutaneous T-cell lymphoma (CTCL)

CU24366

AI-powered CTCL diagnosis tool links genetic markers with EHR data to improve accuracy, staging, and prognosis.

Tags

Assay

Cancer

Cutaneous T cell lymphoma

Inventors

Larisa Geskin

Manager

Cynthia Lang

Departments

Dermatology

Divisions

Columbia University Medical Center (CUMC)

Release Date

2025-01-30

High-throughput single-cell multi-omics platform for integrated RNA, DNA, and protein analysis

CU21072

Integrated single-cell platform enabling high-throughput RNA, DNA, and protein profiling for holistic cellular insights and scalable studies.

Tags

Biomarker

Cell nucleus

Drug discovery

Inventors

Peter A. Sims

Timothy R. Olsen

Manager

Cynthia Lang

Departments

Biochemistry & Molecular Biophysics

Systems Biology

Divisions

Columbia University Medical Center (CUMC)

Release Date

2025-01-02

Collections

Genomics & Multi-Omics

Broadly neutralizing antibody against SARS-CoV-2 variants and related sarbecoviruses

CU24218

Broadly neutralizing antibody targets SARS-CoV-2 variants and related sarbecoviruses, enabling versatile, durable treatment and prophylaxis.

Tags

Antibody

Antiviral drug

Clade

Inventors

David Da-i Ho M.D.

Jian Yu

Lawrence S. Shapiro Ph.D.

Manager

Kristin Neuman

Departments

Aaron Diamond AIDS Research Center (ADARC)

Biochemistry and Molecular Biophysics / Ophthalmology

Medicine

Divisions

Columbia University Medical Center (CUMC)

Release Date

2024-09-16

MicronuclAI: pipeline for automated and reliable micronuclei quantification to assess chromosomal instability

CU24358

MicronuclAI automates and standardizes micronuclei quantification across cell lines, boosting speed, accuracy, and chromosomal instability assessment.

Tags

Cancer

Cell nucleus

Cytogenetics

Inventors

Aroj Hada

Benjamin Izar MD, PhD

Denis Schapiro

Manager

Joan Martinez

Departments

Institute for Computational Biomedicine

Medicine

Program in Cellular, Molecular, Structural and Genetic Studies

Divisions

Columbia University Medical Center (CUMC)

Faculty of the Arts & Sciences

Release Date

2024-07-05

Sensitive SARS-CoV-2 antigen test

CU21002

Ultra-sensitive SARS-CoV-2 antigen sandwich ELISA using dual nucleocapsid antibodies for rapid, low-viral-load detection.

Tags

Antibody

Antigen

Assay

Inventors

David Da-i Ho M.D.

Lihong Liu

Manager

Kristin Neuman

Departments

Medicine

Physicians & Surgeons

Divisions

Columbia University Medical Center (CUMC)

Release Date

2024-04-25

3D organoids for modeling squamous epithelial pathology and personalized medicine

CU22301

3D squamous epithelial organoids enable patient-specific disease modeling and rapid, predictive drug testing for ESCC/EAC.

Tags

Adenocarcinoma

Carcinoma

Epithelium

Inventors

Anil K. Rustgi M.D.

Hiroshi Nakagawa

Manager

Joan Martinez

Departments

Herbert Irving Comprehensive Cancer Center

Medicine

Divisions

Columbia University Medical Center (CUMC)

Release Date

2024-01-04

Collections

Oncology

Clinical decision tool for HIV testing in dental settings

CU24031

Integrated dental EHR prompts HIV screening, streamlining point-of-care testing to broaden access and awareness.

Tags

AIDS

Electronic health record

HIV

Inventors

Sharon Perelman

Tunaidi Ansari

Manager

Joan Martinez

Departments

College of Dental Medicine

Divisions

Columbia University Medical Center (CUMC)

Release Date

2023-11-30

Collections

Medical Device

Digital Health (Software, AI, bioinformatics, etc)

Transgenic zebrafish lines for Alzheimer’s disease models

CU23304

Transgenic zebrafish expressing amyloid beta and Tau model Alzheimer's pathology for in vivo drug screening and biomarker research.

Tags

Amyloid beta

Biomarker

Drug development

Inventors

Caghan Kizil

Manager

Joan Martinez

Departments

Neurology

Divisions

Columbia University Medical Center (CUMC)

Release Date

2023-09-25

Collections

CNS/Neurology

Conditional knockout mouse model for the Phf6 gene

CU22370

A tissue-specific Phf6 conditional knockout mouse model for studying Börjeson-Forssman-Lehmann syndrome and hematologic cancers.

Tags

Acute myeloid leukemia

Gene

High-throughput screening

Inventors

Adolfo A. Ferrando M.D., Ph.D.

Teresa Palomero Vasquez

Manager

Joan Martinez

Departments

Institute for Cancer Genetics

Pathology

Divisions

Columbia University Medical Center (CUMC)

College of Physicians and Surgeons (CUMC)

Release Date

2022-08-20

Disease-in-a-dish model of neuropsychiatric diseases for high-throughput therapeutic screening

CU20125

In vitro hiPSC SETD1A-mutant platform enables high-throughput neuropsychiatric drug screening and pathway discovery.

Tags

Amyotrophic lateral sclerosis

Autism

Enzyme

Inventors

Bin Xu

Joseph A. Gogos

Manager

Joan Martinez

Departments

Physiology and Cellular Biophysics

Psychiatry

Divisions

Columbia University Medical Center (CUMC)

Release Date

2020-10-02

Collections

CNS/Neurology

Platform/Research Tool

NAPA-ID: a proximity-based system to decode protein-protein interactions

CU26166

NAPA-ID enables antibody-guided, proximity labeling of protein interactions without genetic editing, compatible with standard proteomics workflows.

Tags

Antibody

Biological engineering

Biomarker

Inventors

Jeremy Cartalas

Sara Zaccara

Manager

Jerry Kokoshka

Departments

Systems Biology

Divisions

Columbia University Medical Center (CUMC)

Release Date

2026-02-17

Biofluid preparation method for chemical analysis

CU26156

Three-component chromatography column enables rapid, affordable biofluid cleanup for mass spectrometry, boosting throughput and automation.

Tags

Body fluid

Chromatography

Food safety

Inventors

Mazdak M. Bradberry

Manager

Jerry Kokoshka

Departments

Psychiatry

Divisions

Columbia University Medical Center (CUMC)

Release Date

2026-02-17

Compact RNA-guided DNA targeting, cleavage, and transcriptional activation

CU23100

Compact RNA-guided DNA targeting with Cas12/TnpB family enables programmable, compact gene regulation via binding, cleavage, or transcription activation.

Tags

Artificial intelligence

Escherichia coli

Exaptation

Inventors

Chance Meers

Samuel H. Sternberg

Manager

Cynthia Lang

Departments

Biochemistry & Molecular Biophysics

Divisions

Columbia University Medical Center (CUMC)

Release Date

2026-02-17

Programmable CRISPR-transposon platform for targeted DNA insertion

CU23140

CRISPR-CAST enables programmable, cut-free DNA insertion at precise genomic sites, improving safety and efficiency in mammalian cells.

Tags

Genome

Transposable element

Inventors

George Davis Lampe

Samuel H. Sternberg

Manager

Cynthia Lang

Departments

Biochemistry & Molecular Biophysics

Divisions

Columbia University Medical Center (CUMC)

Release Date

2026-01-09

Collections

Genomics & Multi-Omics

Radiomic harmonization tool for multicenter disease studies

Proxy118

Advanced radiomic harmonization: data-driven, multi-source correction across scanners to boost cross-site biomarker reliability.

Tags

Algorithm

Biomarker

CT scan

Inventors

Despina Kontos

Hannah Horng

Russell Shinohara

Manager

Joan Martinez

Departments

Bioengineering

Biostatistics, Epidemiology and Informatics

Radiology

Divisions

Columbia University Medical Center (CUMC)

Release Date

2025-12-04

AI-powered breast density assessment for improved cancer risk prediction

Proxy117

AI-driven Deep-LIBRA quantifies breast density with spatial maps, improving risk prediction and enabling open, validated research tools.

Tags

Artificial intelligence

Breast

Breast cancer

Inventors

Despina Kontos

Omid Haji Maghsoudia

Manager

Joan Martinez

Departments

Radiology

Divisions

Columbia University Medical Center (CUMC)

Release Date

2025-12-04

Deep learning framework for generating nonfat-suppressed MR images from fat-suppressed scans

CU26094

Sat2Nu: a U-Net framework converts fat-suppressed breast MRIs into nonfat-suppressed images, boosting diagnostic workflow without extra scans.

Tags

Adipose tissue

Breast cancer

Deep learning

Inventors

Despina Kontos

Kalina Slavkova

Manager

Joan Martinez

Departments

Radiology

Divisions

Columbia University Medical Center (CUMC)

Release Date

2025-12-01

Colorectal cancer organoid model for therapeutic testing

CU26010

Patient-derived 3D colorectal cancer organoids enable precise drug screening, personalized therapy, and biomarker discovery.

Tags

Colorectal cancer

Extracellular matrix

High-throughput screening

Inventors

Casidhe-Nicole Bethancourt

David Cohen

Joel T. Gabre MD

Manager

Joan Martinez

Departments

Herbert Irving Comprehensive Cancer Center

Medicine

Surgery

Divisions

Columbia University Medical Center (CUMC)

Release Date

2025-10-09

SUMO2 conjugation therapy for restoring cognitive function in Alzheimer's disease

CU23265

SUMO2-based biologic restores synaptic function and memory in Alzheimer's without reducing amyloid, enabling late-stage cognitive recovery.

Tags

Adjuvant therapy

Amyloid beta

Blood–brain barrier

Inventors

Luana Fioriti Ph.D.

Ottavio Arancio

Paul Edward Fraser

Manager

Jerry Kokoshka

Departments

Mortimer B. Zuckerman Mind Brain Behavior Institute

Pathology

Divisions

Columbia University Medical Center (CUMC)

Release Date

2025-06-26

Machine-learning algorithm to improve disease diagnosis using magnetic resonance spectroscopy

CU24256

A deep learning system automates and speeds up in vivo metabolite quantification from MRS, improving disease diagnosis with telecoms-ready MRI integration.

Tags

Algorithm

Deep learning

Dementia

Inventors

Christopher Wu

Jia Guo

Scott A. Small M.D.

Manager

Jerry Kokoshka

Departments

Biomedical Engineering

Neurology

Psychiatry

Divisions

Columbia University Medical Center (CUMC)

Fu Foundation School of Engineering and Applied Science (SEAS)

Release Date

2025-05-30

Human-informed artificial intelligence system for enhanced eye disease detection

CU23260

Expert-eye-movement informed AI enhances glaucoma, AMD detection with interpretable, trainee-friendly, weakly supervised vision transformers.

Tags

Artificial intelligence

Convolutional neural network

Deep learning

Inventors

George Cioffi

Kaveri Thakoor

Manager

Dovina Qu

Departments

Ophthalmology

Divisions

Columbia University Medical Center (CUMC)

Release Date

2025-04-21

Quantitative measurement of eye and head movements for the diagnosis of traumatic brain injury and neurodegeneration

CU21135

Quantitative eye-head movement tracking diagnoses concussion and neurodegeneration, enabling rapid, objective tremor-based brain injury assessment.

Tags

Biomarker

Case–control study

Cognitive deficit

Inventors

Christopher Driscoll

Linus Sun

Thomas Bottiglieri

Manager

Joan Martinez

Departments

Institute of Human Nutrition

Ophthalmology

Orthopedic Surgery

Divisions

Columbia University Medical Center (CUMC)

Release Date

2025-04-21

Collections

CNS/Neurology

Method for studying in-cell single-molecule FRET data collected from proteins diffusing at membrane surfaces using wide-field imaging

CU15268

In-cell smFRET tracking links membrane diffusion states with real-time structural dynamics using wide-field imaging and integrated analysis.

Tags

Biophysics

Cell membrane

Confocal microscopy

Inventors

Jonathan Javitch

Khuloud Jaqaman

Peter Geggier

Manager

Jerry Kokoshka

Departments

Biophysics

Psychiatry

Divisions

Columbia University Medical Center (CUMC)

Release Date

2025-03-05

Collections

Platform/Research Tool

Conditional 5-HT1A receptor knockout mouse model for studying antidepressant response

CU25138

Inducible, cell-type specific 5HT1AR knockout mouse model reveals dentate gyrus roles in antidepressant response and mood regulation.

Tags

5-HT receptor

5-HT1A receptor

Antidepressant

Inventors

Rene Hen

Manager

Kristin Neuman

Departments

Pharmacology

Divisions

Columbia University Medical Center (CUMC)

Release Date

2025-02-28

Combination therapies for Diffuse Midline Glioma (DMG) treatment

CU24228

Targeted, MR-driven DMG combination therapy to overcome tumor heterogeneity; predicts and inverts master regulator activity for improved efficacy.

Tags

Central nervous system

Drug development

Glioma

Inventors

Andrea Califano

Ester Calvo Fernandez

Jovana Pavisic

Manager

Joan Martinez

Departments

Biomedical Informatics

Pathology & Cell Biology

Divisions

Columbia University Medical Center (CUMC)

Release Date

2025-01-02

Targeting glial cells for treating myelofibrosis

CU23243

Targeting Sox10+ and ErbB3+ glial cells in bone marrow to slow or halt myelofibrosis progression.

Tags

Aortic dissection

Biomarker

Cell therapy

Inventors

Junsong Zhou

Lei Ding

Shawn Sarkaria

Manager

Kristin Neuman

Departments

Microbiology

Oncology

Rehabilitation & Regenerative Medicine

Divisions

Columbia University Medical Center (CUMC)

Release Date

2024-11-21

Collections

Oncology

Endoscopic imaging device for precise real-time detection of olfactory tissue

CU25003

Real-time spectral endoscopic detection of olfactory epithelium to preserve smell during head/neck surgeries.

Tags

Biopsy

Endoscopy

Epithelium

Inventors

David A. Gudis

Ian F. Caplan

James P. Schuck

Manager

Sara Gusik

Departments

Mechanical Engineering

Otolaryngology

Otolaryngology--Head & Neck Surgery

Divisions

Columbia University Medical Center (CUMC)

Fu Foundation School of Engineering and Applied Science (SEAS)

Release Date

2024-11-08

Multi-lumen microneedle for intracochlear drug delivery and sampling

CU21117

Ultra-sharp multi-lumen microneedles enable simultaneous intracochlear drug delivery and perilymph sampling with zero net volume change.

Tags

Cochlea

Diffusion

Drug delivery

Inventors

Anil Lalwani

Aykut Aksit

Jeffrey W. Kysar

Manager

Dovina Qu

Departments

Mechanical Engineering

Otolaryngology

Divisions

Columbia University Medical Center (CUMC)

Fu Foundation School of Engineering and Applied Science (SEAS)

Release Date

2024-09-26

Targeting a neural fat-sensing pathway for the treatment of obesity

CU22137

Target fat-sensing gut-brain pathway to curb high-fat eating; potential obesity, diabetes, and heart-disease therapeutics.

Tags

Cardiovascular disease

Chronic kidney disease

Drug development

Inventors

Charles S. Zuker

Mengtong Li

Zhengyuan Lu

Manager

Joan Martinez

Departments

Biochemistry & Molecular Biophysics

Biological Sciences

Mortimer B. Zuckerman Mind Brain Behavior Institute

Divisions

Columbia University Medical Center (CUMC)

Faculty of the Arts & Sciences

Release Date

2024-08-01

Combination therapy to increase the efficacy of antibody-drug conjugates in bladder cancer

CU24095

Small molecule reprograms bladder cancer cells to upregulate antigens, boosting antibody-drug conjugate efficacy. 14 words.

Tags

Antibody-drug conjugate

Antigen

Biopharmaceutical

Inventors

John Robert Christin

Michael Shen Ph.D.

Manager

Joan Martinez

Departments

Medicine

Divisions

Columbia University Medical Center (CUMC)

Release Date

2024-07-09

Clinical decision support system using artificial intelligence

CU24273

AI-based CONCERN system converts nurse documentation into early warning predictions, reducing mortality, sepsis, and ICU transfers.

Tags

Artificial intelligence

Clinical trial

EHealth

Inventors

Christopher Knaplund

Kenrick Cato

Sarah Rossetti

Manager

Kristin Neuman

Departments

Biomedical Informatics

Emergency Medicine

Divisions

Columbia University Medical Center (CUMC)

Release Date

2024-07-05

Parameters to maximize nebulized drug delivery to larynx

CU24050

Patient-specific CT-based nebulization parameters optimize aerosol size and velocity to maximize laryngeal drug deposition.

Tags

Aerosol

Drug delivery

Hypersensitivity

Inventors

Michael Pitman MD

Manager

Cynthia Lang

Departments

Otolaryngology

Divisions

Columbia University Medical Center (CUMC)

Release Date

2024-07-05

Multi-target directed ligand drug development pipeline for Alzheimer's Disease

CU23303

A high-throughput, cost-efficient preclinical pipeline synthesizes and tests multi-target ligands for Alzheimer's, using zebrafish models.

Tags

Biomarker

Cholinesterase

Drug development

Inventors

Caghan Kizil

Manager

Joan Martinez

Departments

Neurology

Divisions

Columbia University Medical Center (CUMC)

Release Date

2024-06-21

ARP-154 (HeLa T4+) human cancer cell line generated by gene transfer for AIDS research

CU24290

CD4-expressing HeLa-derived cell line enables AIDS research; facilitates HIV binding studies, drug screening, and therapeutic development.

Tags

AIDS

Antigen

Autoimmune disease

Inventors

Paul J. Maddon

Richard Axel M.D.

Manager

Joan Martinez

Departments

Biochemistry & Molecular Biophysics

Divisions

Columbia University Medical Center (CUMC)

Release Date

2024-05-29

Alcohol-free botanical oral care products

CU18267

Alcohol-free, plant-based oral care formulations deliver rapid antimicrobial action, reducing side effects and environmental impact.

Tags

Anti-inflammatory

Dental floss

Medical device

Inventors

Chathuranga De Silva

Shanta M. Modak Ph.D.

Manager

Cynthia Lang

Departments

Chemical Engineering/Applied Chemistry

Surgery

Divisions

Columbia University Medical Center (CUMC)

Fu Foundation School of Engineering and Applied Science (SEAS)

Release Date

2024-03-26

Collections

Medical Device

Bioengineered human bone marrow model for drug discovery

CU22388

Engineered 3D human bone marrow from iPSCs enables personalized, in vitro drug screening for hematologic diseases and toxicity.

Tags

Anemia

Bone marrow

Crosstalk

Inventors

Adolfo A. Ferrando M.D., Ph.D.

Daniel Naveed Tavakol

Gordana Vunjak-Novakovic

Manager

Cynthia Lang

Departments

Biomedical Engineering

Institute for Cancer Genetics

Pediatrics

Divisions

Columbia University Medical Center (CUMC)

Fu Foundation School of Engineering and Applied Science (SEAS)

Release Date

2024-02-27

Collections

Oncology

Host proteases necessary for human parainfluenza virus spread in human lung

CU22326

Identifies HPIV spread proteases; shows serine protease inhibitors (nafamostat) hinder lung infection, offering targeted antiviral strategy.

Tags

Antiviral drug

Enzyme inhibitor

Evolution

Inventors

Anne Moscona

Kyle Stearns

Matteo Porotto

Manager

Kristin Neuman

Departments

Anesthesiology

Pediatrics

Divisions

Columbia University Medical Center (CUMC)

Release Date

2024-02-15

Robotic system to efficiently handle cell culture plates in embryology laboratories

CU22015

Robotic platform automates high-throughput, contamination-free preparation of embryology cell culture plates, boosting consistency and efficiency.

Tags

Cell culture

Embryo

Embryology

Inventors

Samuel Z. "Zev" Williams

Manager

Cynthia Lang

Departments

Obstetrics & Gynecology

Divisions

Columbia University Medical Center (CUMC)

Release Date

2024-01-13

Gene editing system for the treatment of autosomal dominant disease-related genes

CU18283

Mutation-independent CRISPR pair replaces dominant alleles with a functional gene to treat autosomal dominant diseases.

Tags

CRISPR

Gene therapy

Genetic disorder

Inventors

Stephen H. Tsang M.D., Ph.D.

Wen-Hsuan Wu

Yi-Ting Tsai

Manager

Kristin Neuman

Departments

Nutritional and Metabolic Biology

Ophthalmology

Divisions

Columbia University Medical Center (CUMC)

College of Physicians and Surgeons (CUMC

Faculty of the Arts & Sciences

Release Date

2023-12-28

Collections

Ophthalmology

Gene Therapy