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Columbia University Medical Center (CUMC)

612 results

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Automated MRI-based breast cancer segmentation

CU26095

AI-driven, scalable MRI segmentation for breast cancer (DCIS); automates lesion delineation, boosting speed, consistency, and research utility.

Tags: Biomarker
Breast cancer
Breast cancer screening
Inventors: Despina Kontos
Kalina Slavkova
Manager: Joan Martinez
Departments: Radiology
Divisions: Columbia University Medical Center (CUMC)
Release Date: 2026-02-20

Chimeric CRISPR-associated transposon system for RNA-mediated DNA integration

CU24119

Chimeric CAST enables efficient, RNA-guided DNA insertion without breaks, combining components for larger cargo in cells.

Tags: Coevolution
DNA repair
Enzyme
Inventors: George Davis Lampe
Samuel H. Sternberg
Manager: Cynthia Lang
Departments: Biochemistry & Molecular Biophysics
Divisions: Columbia University Medical Center (CUMC)
Release Date: 2026-01-09
Collections: Genomics & Multi-Omics

Small molecule activators for preventing vision loss in Best vitelliform macular dystrophy

CU25176

Small molecule activators restore Best1 function to slow BVMD vision loss; targeted, potentially non-invasive retinal therapy.

Tags: 4-Aminobenzoic acid
Drug development
Gene therapy
Inventors: Bingchen Yu
Tingting Yang
Yu Zhang
Manager: Joan Martinez
Departments: Chemistry
Ophthalmology
Divisions: Columbia University Medical Center (CUMC)
Release Date: 2025-05-01
Collections: Ophthalmology

Microfluidic platform for large-scale single-cell sequencing and imaging

CU16248

Scalable, low-cost microfluidic platform linking live-cell imaging with single-cell RNA sequencing via optical barcodes.

Tags: Brain mapping
Cell culture
Drug discovery
Inventors: Jinzhou Yuan
Peter A. Sims
Sayantan Bose
Manager: Cynthia Lang
Departments: Biochemistry & Molecular Biophysics
Systems Biology
Divisions: Columbia University Medical Center (CUMC)
Release Date: 2025-01-02
Collections: Genomics & Multi-Omics

Paramyxovirus fusion complex structure for antiviral and vaccine design

CU23202

A conserved paramyxovirus fusion complex structure enables targeted antivirals and vaccine design, stabilizing pre-fusion entry protein.

Tags: Antigen
Antiviral drug
Fusion protein
Inventors: Anne Moscona
Matteo Porotto
Tara Marcink
Manager: Kristin Neuman
Departments: Pediatrics
Divisions: Columbia University Medical Center (CUMC)
Release Date: 2024-02-21

Therapeutic antibodies against amyloid aggregates

CU23354

Antibody platform targets TMEM106B amyloid aggregates for diagnosis, therapeutics, and research across neurodegenerative diseases.

Tags: Amyloid beta
Antibody
Biomarker
Inventors: Anthony William Paul Fitzpatrick
Carolyn Lee
Junqiang Ye Ph.D.
Manager: Kristin Neuman
Departments: Biochemistry
Biochemistry & Molecular Biophysics
Divisions: Columbia University Medical Center (CUMC)
Release Date: 2026-02-26

tomoLIBRA: Deep learning software for automated volumetric breast density estimation

CU26015

AI-based tomoLIBRA estimates volumetric breast density from standard 3D DBT images, enabling scalable, retrospective risk assessment without raw data.

Tags: Breast cancer
Breast cancer screening
Case–control study
Inventors: Aimilia Gastounioti
Ari Brooks
Celine Vachon
Manager: Joan Martinez
Departments: Biomedical Engineering
Radiology
Divisions: Columbia University Medical Center (CUMC)
Fu Foundation School of Engineering and Applied Science (SEAS)
School of Medicine
Release Date: 2026-02-20

Digital addiction monitoring and early mental health intervention platform

CU26164

Passive, trajectory-based digital addiction monitoring with adaptive mental-health interventions to preempt crises and escalate care.

Tags: Cohort study
Major depressive disorder
Mental health
Inventors: J. John Mann
Yunyu Xiao
Manager: Jerry Kokoshka
Departments: Psychiatry
Divisions: Columbia University Medical Center (CUMC)
Release Date: 2026-02-17

Encryption method for secure storage and analysis of patient data on the cloud

CU24094

A cloud-friendly, privacy-preserving genomic analysis method using homomorphic encryption to enable multi-user queries on encrypted patient data.

Tags: Ciphertext
Cloud computing
Data management
Inventors: Gamze Gursoy
Jacob Blindenbach
Jiayi Kang
Manager: Joan Martinez
Departments: Biomedical Informatics
Computer Science
Divisions: Columbia University Medical Center (CUMC)
Fu Foundation School of Engineering and Applied Science (SEAS)
Release Date: 2026-02-03

WDFY3 variant mouse models for neurodegenerative studies

CU26145

A clinically relevant WDFY3 knock-in mouse model to study autophagy’s role in neurodegenerative diseases and therapies.

Tags: Autophagy
Neurodegenerative disease
Neuron
Inventors: Ai Yamamoto
Manager: Kristin Neuman
Departments: Physiology and Cellular Biophysics
Divisions: Columbia University Medical Center (CUMC)
Release Date: 2026-01-08

Artificial intelligence tool for rapid, automated electronic health record review

CU26003

AI-powered OphthoACR automates rapid, accurate ophthalmology EHR data extraction from unstructured notes and imaging.

Tags: Abstraction (computer science)
Artificial intelligence
Cohort study
Inventors: Karen Chen
Leejee Han Suh
Vlad Diaconita
Manager: Kristin Neuman
Departments: Ophthalmology
Physicians & Surgeons
Divisions: Columbia University Medical Center (CUMC)
Release Date: 2025-10-23

Machine learning tool for diagnosis of cutaneous T-cell lymphoma (CTCL)

CU24366

AI-powered CTCL diagnosis tool links genetic markers with EHR data to improve accuracy, staging, and prognosis.

Tags: Assay
Cancer
Cutaneous T cell lymphoma
Inventors: Larisa Geskin
Manager: Cynthia Lang
Departments: Dermatology
Divisions: Columbia University Medical Center (CUMC)
Release Date: 2025-01-30

High-throughput single-cell multi-omics platform for integrated RNA, DNA, and protein analysis

CU21072

Integrated single-cell platform enabling high-throughput RNA, DNA, and protein profiling for holistic cellular insights and scalable studies.

Tags: Biomarker
Cell nucleus
Drug discovery
Inventors: Peter A. Sims
Timothy R. Olsen
Manager: Cynthia Lang
Departments: Biochemistry & Molecular Biophysics
Systems Biology
Divisions: Columbia University Medical Center (CUMC)
Release Date: 2025-01-02
Collections: Genomics & Multi-Omics

Broadly neutralizing antibody against SARS-CoV-2 variants and related sarbecoviruses

CU24218

Broadly neutralizing antibody targets SARS-CoV-2 variants and related sarbecoviruses, enabling versatile, durable treatment and prophylaxis.

Tags: Antibody
Antiviral drug
Clade
Inventors: David Da-i Ho M.D.
Jian Yu
Lawrence S. Shapiro Ph.D.
Manager: Kristin Neuman
Departments: Aaron Diamond AIDS Research Center (ADARC)
Biochemistry and Molecular Biophysics / Ophthalmology
Medicine
Divisions: Columbia University Medical Center (CUMC)
Release Date: 2024-09-16

MicronuclAI: pipeline for automated and reliable micronuclei quantification to assess chromosomal instability

CU24358

MicronuclAI automates and standardizes micronuclei quantification across cell lines, boosting speed, accuracy, and chromosomal instability assessment.

Tags: Cancer
Cell nucleus
Cytogenetics
Inventors: Aroj Hada
Benjamin Izar MD, PhD
Denis Schapiro
Manager: Joan Martinez
Departments: Institute for Computational Biomedicine
Medicine
Program in Cellular, Molecular, Structural and Genetic Studies
Divisions: Columbia University Medical Center (CUMC)
Faculty of the Arts & Sciences
Release Date: 2024-07-05

Sensitive SARS-CoV-2 antigen test

CU21002

Ultra-sensitive SARS-CoV-2 antigen sandwich ELISA using dual nucleocapsid antibodies for rapid, low-viral-load detection.

Tags: Antibody
Antigen
Assay
Inventors: David Da-i Ho M.D.
Lihong Liu
Manager: Kristin Neuman
Departments: Medicine
Physicians & Surgeons
Divisions: Columbia University Medical Center (CUMC)
Release Date: 2024-04-25

3D organoids for modeling squamous epithelial pathology and personalized medicine

CU22301

3D squamous epithelial organoids enable patient-specific disease modeling and rapid, predictive drug testing for ESCC/EAC.

Tags: Adenocarcinoma
Carcinoma
Epithelium
Inventors: Anil K. Rustgi M.D.
Hiroshi Nakagawa
Manager: Joan Martinez
Departments: Herbert Irving Comprehensive Cancer Center
Medicine
Divisions: Columbia University Medical Center (CUMC)
Release Date: 2024-01-04
Collections: Oncology

Clinical decision tool for HIV testing in dental settings

CU24031

Integrated dental EHR prompts HIV screening, streamlining point-of-care testing to broaden access and awareness.

Tags: AIDS
Electronic health record
HIV
Inventors: Sharon Perelman
Tunaidi Ansari
Manager: Joan Martinez
Departments: College of Dental Medicine
Divisions: Columbia University Medical Center (CUMC)
Release Date: 2023-11-30
Collections: Medical Device
Digital Health (Software, AI, bioinformatics, etc)

Transgenic zebrafish lines for Alzheimer’s disease models

CU23304

Transgenic zebrafish expressing amyloid beta and Tau model Alzheimer's pathology for in vivo drug screening and biomarker research.

Tags: Amyloid beta
Biomarker
Drug development
Inventors: Caghan Kizil
Manager: Joan Martinez
Departments: Neurology
Divisions: Columbia University Medical Center (CUMC)
Release Date: 2023-09-25
Collections: CNS/Neurology

Conditional knockout mouse model for the Phf6 gene

CU22370

A tissue-specific Phf6 conditional knockout mouse model for studying Börjeson-Forssman-Lehmann syndrome and hematologic cancers.

Tags: Acute myeloid leukemia
Gene
High-throughput screening
Inventors: Adolfo A. Ferrando M.D., Ph.D.
Teresa Palomero Vasquez
Manager: Joan Martinez
Departments: Institute for Cancer Genetics
Pathology
Divisions: Columbia University Medical Center (CUMC)
College of Physicians and Surgeons (CUMC)
Release Date: 2022-08-20

Disease-in-a-dish model of neuropsychiatric diseases for high-throughput therapeutic screening

CU20125

In vitro hiPSC SETD1A-mutant platform enables high-throughput neuropsychiatric drug screening and pathway discovery.

Tags: Amyotrophic lateral sclerosis
Autism
Enzyme
Inventors: Bin Xu
Joseph A. Gogos
Manager: Joan Martinez
Departments: Physiology and Cellular Biophysics
Psychiatry
Divisions: Columbia University Medical Center (CUMC)
Release Date: 2020-10-02
Collections: CNS/Neurology
Platform/Research Tool

Surgical imaging device for minimally invasive surgery

2381

An insertable, stereoscopic surgical imaging device enabling single-port, fully internal visualization with pan-tilt-zoom and lighting.

Tags: Depth perception
Laparoscopy
Lens
Inventors: Dennis Fowler
Peter Allen
Manager: Kristin Neuman
Departments: Computer Science
Surgery
Divisions: Columbia University Medical Center (CUMC)
Fu Foundation School of Engineering and Applied Science (SEAS)
Release Date: 2026-03-06

NAPA-ID: a proximity-based system to decode protein-protein interactions

CU26166

NAPA-ID enables antibody-guided, proximity labeling of protein interactions without genetic editing, compatible with standard proteomics workflows.

Tags: Antibody
Biological engineering
Biomarker
Inventors: Jeremy Cartalas
Sara Zaccara
Manager: Jerry Kokoshka
Departments: Systems Biology
Divisions: Columbia University Medical Center (CUMC)
Release Date: 2026-02-17

Biofluid preparation method for chemical analysis

CU26156

Three-component chromatography column enables rapid, affordable biofluid cleanup for mass spectrometry, boosting throughput and automation.

Tags: Body fluid
Chromatography
Food safety
Inventors: Mazdak M. Bradberry
Manager: Jerry Kokoshka
Departments: Psychiatry
Divisions: Columbia University Medical Center (CUMC)
Release Date: 2026-02-17

Compact RNA-guided DNA targeting, cleavage, and transcriptional activation

CU23100

Compact RNA-guided DNA targeting with Cas12/TnpB family enables programmable, compact gene regulation via binding, cleavage, or transcription activation.

Tags: Artificial intelligence
Escherichia coli
Exaptation
Inventors: Chance Meers
Samuel H. Sternberg
Manager: Cynthia Lang
Departments: Biochemistry & Molecular Biophysics
Divisions: Columbia University Medical Center (CUMC)
Release Date: 2026-02-17

Programmable CRISPR-transposon platform for targeted DNA insertion

CU23140

CRISPR-CAST enables programmable, cut-free DNA insertion at precise genomic sites, improving safety and efficiency in mammalian cells.

Tags: Genome
Transposable element
Inventors: George Davis Lampe
Samuel H. Sternberg
Manager: Cynthia Lang
Departments: Biochemistry & Molecular Biophysics
Divisions: Columbia University Medical Center (CUMC)
Release Date: 2026-01-09
Collections: Genomics & Multi-Omics

Radiomic harmonization tool for multicenter disease studies

Proxy118

Advanced radiomic harmonization: data-driven, multi-source correction across scanners to boost cross-site biomarker reliability.

Tags: Algorithm
Biomarker
CT scan
Inventors: Despina Kontos
Hannah Horng
Russell Shinohara
Manager: Joan Martinez
Departments: Bioengineering
Biostatistics, Epidemiology and Informatics
Radiology
Divisions: Columbia University Medical Center (CUMC)
Release Date: 2025-12-04

AI-powered breast density assessment for improved cancer risk prediction

Proxy117

AI-driven Deep-LIBRA quantifies breast density with spatial maps, improving risk prediction and enabling open, validated research tools.

Tags: Artificial intelligence
Breast
Breast cancer
Inventors: Despina Kontos
Omid Haji Maghsoudia
Manager: Joan Martinez
Departments: Radiology
Divisions: Columbia University Medical Center (CUMC)
Release Date: 2025-12-04

Deep learning framework for generating nonfat-suppressed MR images from fat-suppressed scans

CU26094

Sat2Nu: a U-Net framework converts fat-suppressed breast MRIs into nonfat-suppressed images, boosting diagnostic workflow without extra scans.

Tags: Adipose tissue
Breast cancer
Deep learning
Inventors: Despina Kontos
Kalina Slavkova
Manager: Joan Martinez
Departments: Radiology
Divisions: Columbia University Medical Center (CUMC)
Release Date: 2025-12-01

Colorectal cancer organoid model for therapeutic testing

CU26010

Patient-derived 3D colorectal cancer organoids enable precise drug screening, personalized therapy, and biomarker discovery.

Tags: Colorectal cancer
Extracellular matrix
High-throughput screening
Inventors: Casidhe-Nicole Bethancourt
David Cohen
Joel T. Gabre MD
Manager: Joan Martinez
Departments: Herbert Irving Comprehensive Cancer Center
Medicine
Surgery
Divisions: Columbia University Medical Center (CUMC)
Release Date: 2025-10-09

SUMO2 conjugation therapy for restoring cognitive function in Alzheimer's disease

CU23265

SUMO2-based biologic restores synaptic function and memory in Alzheimer's without reducing amyloid, enabling late-stage cognitive recovery.

Tags: Adjuvant therapy
Amyloid beta
Blood–brain barrier
Inventors: Luana Fioriti Ph.D.
Ottavio Arancio
Paul Edward Fraser
Manager: Jerry Kokoshka
Departments: Mortimer B. Zuckerman Mind Brain Behavior Institute
Pathology
Divisions: Columbia University Medical Center (CUMC)
Release Date: 2025-06-26

Machine-learning algorithm to improve disease diagnosis using magnetic resonance spectroscopy

CU24256

A deep learning system automates and speeds up in vivo metabolite quantification from MRS, improving disease diagnosis with telecoms-ready MRI integration.

Tags: Algorithm
Deep learning
Dementia
Inventors: Christopher Wu
Jia Guo
Scott A. Small M.D.
Manager: Jerry Kokoshka
Departments: Biomedical Engineering
Neurology
Psychiatry
Divisions: Columbia University Medical Center (CUMC)
Fu Foundation School of Engineering and Applied Science (SEAS)
Release Date: 2025-05-30

Human-informed artificial intelligence system for enhanced eye disease detection

CU23260

Expert-eye-movement informed AI enhances glaucoma, AMD detection with interpretable, trainee-friendly, weakly supervised vision transformers.

Tags: Artificial intelligence
Convolutional neural network
Deep learning
Inventors: George Cioffi
Kaveri Thakoor
Manager: Dovina Qu
Departments: Ophthalmology
Divisions: Columbia University Medical Center (CUMC)
Release Date: 2025-04-21

Quantitative measurement of eye and head movements for the diagnosis of traumatic brain injury and neurodegeneration

CU21135

Quantitative eye-head movement tracking diagnoses concussion and neurodegeneration, enabling rapid, objective tremor-based brain injury assessment.

Tags: Biomarker
Case–control study
Cognitive deficit
Inventors: Christopher Driscoll
Linus Sun
Thomas Bottiglieri
Manager: Joan Martinez
Departments: Institute of Human Nutrition
Ophthalmology
Orthopedic Surgery
Divisions: Columbia University Medical Center (CUMC)
Release Date: 2025-04-21
Collections: CNS/Neurology

Method for studying in-cell single-molecule FRET data collected from proteins diffusing at membrane surfaces using wide-field imaging

CU15268

In-cell smFRET tracking links membrane diffusion states with real-time structural dynamics using wide-field imaging and integrated analysis.

Tags: Biophysics
Cell membrane
Confocal microscopy
Inventors: Jonathan Javitch
Khuloud Jaqaman
Peter Geggier
Manager: Jerry Kokoshka
Departments: Biophysics
Psychiatry
Divisions: Columbia University Medical Center (CUMC)
Release Date: 2025-03-05
Collections: Platform/Research Tool

Conditional 5-HT1A receptor knockout mouse model for studying antidepressant response

CU25138

Inducible, cell-type specific 5HT1AR knockout mouse model reveals dentate gyrus roles in antidepressant response and mood regulation.

Tags: 5-HT receptor
5-HT1A receptor
Antidepressant
Inventors: Rene Hen
Manager: Kristin Neuman
Departments: Pharmacology
Divisions: Columbia University Medical Center (CUMC)
Release Date: 2025-02-28

Combination therapies for Diffuse Midline Glioma (DMG) treatment

CU24228

Targeted, MR-driven DMG combination therapy to overcome tumor heterogeneity; predicts and inverts master regulator activity for improved efficacy.

Tags: Central nervous system
Drug development
Glioma
Inventors: Andrea Califano
Ester Calvo Fernandez
Jovana Pavisic
Manager: Joan Martinez
Departments: Biomedical Informatics
Pathology & Cell Biology
Divisions: Columbia University Medical Center (CUMC)
Release Date: 2025-01-02

Targeting glial cells for treating myelofibrosis

CU23243

Targeting Sox10+ and ErbB3+ glial cells in bone marrow to slow or halt myelofibrosis progression.

Tags: Aortic dissection
Biomarker
Cell therapy
Inventors: Junsong Zhou
Lei Ding
Shawn Sarkaria
Manager: Kristin Neuman
Departments: Microbiology
Oncology
Rehabilitation & Regenerative Medicine
Divisions: Columbia University Medical Center (CUMC)
Release Date: 2024-11-21
Collections: Oncology

Endoscopic imaging device for precise real-time detection of olfactory tissue

CU25003

Real-time spectral endoscopic detection of olfactory epithelium to preserve smell during head/neck surgeries.

Tags: Biopsy
Endoscopy
Epithelium
Inventors: David A. Gudis
Ian F. Caplan
James P. Schuck
Manager: Sara Gusik
Departments: Mechanical Engineering
Otolaryngology
Otolaryngology--Head & Neck Surgery
Divisions: Columbia University Medical Center (CUMC)
Fu Foundation School of Engineering and Applied Science (SEAS)
Release Date: 2024-11-08

Multi-lumen microneedle for intracochlear drug delivery and sampling

CU21117

Ultra-sharp multi-lumen microneedles enable simultaneous intracochlear drug delivery and perilymph sampling with zero net volume change.

Tags: Cochlea
Diffusion
Drug delivery
Inventors: Anil Lalwani
Aykut Aksit
Jeffrey W. Kysar
Manager: Dovina Qu
Departments: Mechanical Engineering
Otolaryngology
Divisions: Columbia University Medical Center (CUMC)
Fu Foundation School of Engineering and Applied Science (SEAS)
Release Date: 2024-09-26

Targeting a neural fat-sensing pathway for the treatment of obesity

CU22137

Target fat-sensing gut-brain pathway to curb high-fat eating; potential obesity, diabetes, and heart-disease therapeutics.

Tags: Cardiovascular disease
Chronic kidney disease
Drug development
Inventors: Charles S. Zuker
Mengtong Li
Zhengyuan Lu
Manager: Joan Martinez
Departments: Biochemistry & Molecular Biophysics
Biological Sciences
Mortimer B. Zuckerman Mind Brain Behavior Institute
Divisions: Columbia University Medical Center (CUMC)
Faculty of the Arts & Sciences
Release Date: 2024-08-01

Combination therapy to increase the efficacy of antibody-drug conjugates in bladder cancer

CU24095

Small molecule reprograms bladder cancer cells to upregulate antigens, boosting antibody-drug conjugate efficacy. 14 words.

Tags: Antibody-drug conjugate
Antigen
Biopharmaceutical
Inventors: John Robert Christin
Michael Shen Ph.D.
Manager: Joan Martinez
Departments: Medicine
Divisions: Columbia University Medical Center (CUMC)
Release Date: 2024-07-09

Clinical decision support system using artificial intelligence

CU24273

AI-based CONCERN system converts nurse documentation into early warning predictions, reducing mortality, sepsis, and ICU transfers.

Tags: Artificial intelligence
Clinical trial
EHealth
Inventors: Christopher Knaplund
Kenrick Cato
Sarah Rossetti
Manager: Kristin Neuman
Departments: Biomedical Informatics
Emergency Medicine
Divisions: Columbia University Medical Center (CUMC)
Release Date: 2024-07-05

Parameters to maximize nebulized drug delivery to larynx

CU24050

Patient-specific CT-based nebulization parameters optimize aerosol size and velocity to maximize laryngeal drug deposition.

Tags: Aerosol
Drug delivery
Hypersensitivity
Inventors: Michael Pitman MD
Manager: Cynthia Lang
Departments: Otolaryngology
Divisions: Columbia University Medical Center (CUMC)
Release Date: 2024-07-05

Multi-target directed ligand drug development pipeline for Alzheimer's Disease

CU23303

A high-throughput, cost-efficient preclinical pipeline synthesizes and tests multi-target ligands for Alzheimer's, using zebrafish models.

Tags: Biomarker
Cholinesterase
Drug development
Inventors: Caghan Kizil
Manager: Joan Martinez
Departments: Neurology
Divisions: Columbia University Medical Center (CUMC)
Release Date: 2024-06-21

ARP-154 (HeLa T4+) human cancer cell line generated by gene transfer for AIDS research

CU24290

CD4-expressing HeLa-derived cell line enables AIDS research; facilitates HIV binding studies, drug screening, and therapeutic development.

Tags: AIDS
Antigen
Autoimmune disease
Inventors: Paul J. Maddon
Richard Axel M.D.
Manager: Joan Martinez
Departments: Biochemistry & Molecular Biophysics
Divisions: Columbia University Medical Center (CUMC)
Release Date: 2024-05-29

Alcohol-free botanical oral care products

CU18267

Alcohol-free, plant-based oral care formulations deliver rapid antimicrobial action, reducing side effects and environmental impact.

Tags: Anti-inflammatory
Dental floss
Medical device
Inventors: Chathuranga De Silva
Shanta M. Modak Ph.D.
Manager: Cynthia Lang
Departments: Chemical Engineering/Applied Chemistry
Surgery
Divisions: Columbia University Medical Center (CUMC)
Fu Foundation School of Engineering and Applied Science (SEAS)
Release Date: 2024-03-26
Collections: Medical Device

Bioengineered human bone marrow model for drug discovery

CU22388

Engineered 3D human bone marrow from iPSCs enables personalized, in vitro drug screening for hematologic diseases and toxicity.

Tags: Anemia
Bone marrow
Crosstalk
Inventors: Adolfo A. Ferrando M.D., Ph.D.
Daniel Naveed Tavakol
Gordana Vunjak-Novakovic
Manager: Cynthia Lang
Departments: Biomedical Engineering
Institute for Cancer Genetics
Pediatrics
Divisions: Columbia University Medical Center (CUMC)
Fu Foundation School of Engineering and Applied Science (SEAS)
Release Date: 2024-02-27
Collections: Oncology

Host proteases necessary for human parainfluenza virus spread in human lung

CU22326

Identifies HPIV spread proteases; shows serine protease inhibitors (nafamostat) hinder lung infection, offering targeted antiviral strategy.

Tags: Antiviral drug
Enzyme inhibitor
Evolution
Inventors: Anne Moscona
Kyle Stearns
Matteo Porotto
Manager: Kristin Neuman
Departments: Anesthesiology
Pediatrics
Divisions: Columbia University Medical Center (CUMC)
Release Date: 2024-02-15

Robotic system to efficiently handle cell culture plates in embryology laboratories

CU22015

Robotic platform automates high-throughput, contamination-free preparation of embryology cell culture plates, boosting consistency and efficiency.

Tags: Cell culture
Embryo
Embryology
Inventors: Samuel Z. "Zev" Williams
Manager: Cynthia Lang
Departments: Obstetrics & Gynecology
Divisions: Columbia University Medical Center (CUMC)
Release Date: 2024-01-13