Compact optical generation of ultra-low-noise microwave signalsCU22190Compact, chip-scale optical oscillators deliver ultra-low-noise microwave signals with built-in noise suppression and no active electronics.TagsAnalogue electronicsData communicationHard disk driveInventorsAlexander GaetaBok Young KimJae JangManagerGreg MaskelDepartmentsElectrical EngineeringApplied Physics & Applied Math (APAM)DivisionsFu Foundation School of Engineering and Applied Science (SEAS)Release Date2026-02-27
Super-resolution microscopy using tunable fluorescent nanodiamondsCU12035Deterministic emitter switch microscopy with tunable fluorescent nanodiamonds enables rapid, 12–15 nm super-resolution imaging and sensing.TagsCharge-coupled deviceConfocal microscopyDiffraction-limited systemInventorsDirk EnglundManagerGreg MaskelDepartmentsElectrical EngineeringDivisionsFu Foundation School of Engineering and Applied Science (SEAS)Release Date2017-04-21
Infrared photonic crystal spectrometerM11-035A compact, robust, no-moving-parts infrared spectrometer using photonic crystal arrays for 2D wavelength resolution.TagsCryogenicsFourier-transform infrared spectroscopyInfrared spectroscopyInventorsJohn Ioannis KymissisMarshall CoxNadia PervezManagerGreg MaskelDepartmentsElectrical EngineeringApplied Physics & Applied Math (APAM)DivisionsFu Foundation School of Engineering and Applied Science (SEAS)Release Date2026-02-14
Scalable software and hardware for deep neural network developmentCU24101Log-normal weight initialization and constrained training for scalable, resource-efficient deep neural networks across architectures.TagsComputer visionDeep learningFacial recognition systemInventorsManasi Gurunath KhandekarN. SanjeevrajanVenkat VenkatasubramanianManagerGreg MaskelDepartmentsElectrical EngineeringChemical Engineering/Applied ChemistryDivisionsFu Foundation School of Engineering and Applied Science (SEAS)Release Date2024-10-25
Enhanced CMOS amplifier nanopore sensor for ion channel analysisCU12278Enhanced CMOS nanopore amplifier boosts high-throughput, high-resolution ion channel sensing for drug discovery and diagnostics. (136 characters)TagsAmplifierCMOSDNA sequencingInventorsJacob RosensteinKenneth ShepardSiddharth Ramakrishnan PhDManagerGreg MaskelDepartmentsElectrical EngineeringDivisionsFu Foundation School of Engineering and Applied Science (SEAS)Release Date2023-11-21
Thermostable microring modulators for use in optical devicesCU14094Thermostable silicon microring modulators with mean-power feedback stabilize resonance, enabling compact, low-power, high-speed optical links.TagsEnergyIntegrated circuitLaserInventorsAndrew KnightsDylan LoganKeren BergmanManagerGreg MaskelDepartmentsElectrical EngineeringDivisionsFu Foundation School of Engineering andFu Foundation School of Engineering and Applied Science (SEAS)Release Date2018-04-13
Adaptive machine learning platform for image-based rapid diagnostic test interpretationCU21034Adaptive AI interprets diverse rapid tests from images with self-supervised pretraining, smartphone-ready and scalable.TagsArtificial neural networkMachine learningQuality controlInventorsDavid ColburnGuangxing HanJiawei MaManagerDovina QuDepartmentsElectrical EngineeringBiomedical EngineeringComputer ScienceDivisionsFu Foundation School of Engineering and Applied Science (SEAS)Release Date2026-02-14
Brain-informed speech separation (BISS) for auditory speech signal enhancementCU21093Brain-informed speech separation (BISS) uses neural signals and deep learning to isolate and enhance target speech in noisy environments.TagsActive noise controlElectroencephalographyHearing lossInventorsEnea CeoliniNima MesgaraniManagerKristin NeumanDepartmentsElectrical EngineeringMortimer B. Zuckerman Mind Brain Behavior InstituteDivisionsFu Foundation School of Engineering and Applied Science (SEAS)Release Date2025-11-20
Scalable and modular multilevel power convertersCU21174A scalable, voltage-balanced, modular multilevel power converter topology enabling bidirectional AC/DC/DC-DC conversion with linear cell scalability.TagsControllabilityElectric vehicleHigh voltageInventorsMatthew JahnesMatthias Preindl PhDManagerGreg MaskelDepartmentsElectrical EngineeringDivisionsFu Foundation School of Engineering and Applied Science (SEAS)Release Date2023-09-18
Model for characterizing lithium-ion battery overpotentialsCU23074A four-parameter Li-ion overpotential model improves accuracy, monitoring, and maximum power estimation by capturing diffusion dynamics.TagsDiffusionElectric batteryEnergyInventorsAlan Gen LiMatthias Preindl PhDManagerGreg MaskelDepartmentsElectrical EngineeringDivisionsFu Foundation School of Engineering and Applied Science (SEAS)Release Date2023-08-23
Phase interpolator for efficient serial data communicationCU22025Twin phase interpolators with a delta quadrature DLL enable wideband, low-noise, high-linearity, low-power serial data links.Tags65 nm processBasebandCMOSInventorsPeter KingetZhaowen WangManagerGreg MaskelDepartmentsElectrical EngineeringDivisionsFu Foundation School of Engineering and Applied Science (SEAS)Release Date2023-01-31
Complete amplitude and phase spatial light modulation via miniature optical resonatorsCU19263High-precision, low-power, full-amplitude and phase optical modulation on a micrometer-scale photonic chip for visible to telecom bands.TagsAmplitudeAmplitude modulationAugmented realityInventorsGuozhen LiangHeqing HuangMichal LipsonManagerGreg MaskelDepartmentsElectrical EngineeringApplied Physics & Applied MathApplied Physics & Applied Math (APAM)DivisionsFu Foundation School of Engineering and Applied Science (SEAS)Release Date2022-11-09
Real-time guidance of RFA catheter contact orientationCU19041Real-time OCT-guided RFA catheter placement with contact/orientation visualization, boosting accuracy and lesion quality.TagsCatheterContact angleLesionInventorsChristine P. HendonCindy YuRajinder Singh-MoonManagerDovina QuDepartmentsElectrical EngineeringBiomedical EngineeringDivisionsFu Foundation School of Engineering and Applied Science (SEAS)Release Date2020-12-02CollectionsCardiovascular
Scanning electrochemical microscope for efficient nanoscopic imaging over macroscopic areasCU17170Non-local scanning probes plus compressed sensing accelerate nanoscopic imaging across large areas, boosting speed without sacrificing resolution.TagsAtrophyMacular degenerationPhenotypeInventorsDaniel Vincent EspositoGlen Daniel O'NeilHan-wen KuoManagerDovina QuDepartmentsElectrical EngineeringChemical Engineering/Applied ChemistryColumbia Technology VenturesDivisionsFu Foundation School of Engineering and Applied Science (SEAS)MorningsideRelease Date2019-01-25
System for detection and amplification of target speech in multi-talker environmentsCU17276Brainwave-guided real-time speech separation amplifies attended speaker in multi-talker scenes, aiding hearing-impaired listeners.TagsAttractorNoise reductionSpeech perceptionInventorsNima MesgaraniYi LuoZhuo ChenManagerKristin NeumanDepartmentsElectrical EngineeringDivisionsFu Foundation School of Engineering and Applied Science (SEAS)Release Date2017-06-08
Object-based audio-visual terminal and bitstream structureMS96/01/27Object-based AV system stores, transmits, and composes video from persistent AV objects across separate channels with lifetime persistence.TagsCPU cacheObject databaseInventorsAlexandros EleftheriadisManagerJim AloiseDepartmentsElectrical EngineeringDivisionsFu Foundation School of Engineering and Applied Science (SEAS)
High-performance tensor-train primitives on graphics processorsCU24167GPU-tensor core toolkit speeds tensor-train ops, multi-GPU scaling, and neural-network compression with efficient data movement.TagsComputational scienceGraphics processing unitHardware accelerationInventorsXiaodong WangXiaoyang LiuManagerGreg MaskelDepartmentsElectrical EngineeringDivisionsFu Foundation School of Engineering and Applied Science (SEAS)Release Date2026-03-06
Robust and efficient visual motion detection based on Fast Fourier Transform and phase-based algorithmsCU15252Phase-based FFT visual motion detector: fast, robust under low light and noise, enabling reliable motion detection across devices.TagsAlgorithmAugmented realityFast Fourier transformInventorsAurel LazarNikul H. UkaniYiyin ZhouManagerGreg MaskelDepartmentsElectrical EngineeringDivisionsFu Foundation School of Engineering and Applied Science (SEAS)Release Date2025-10-23
Machine learning-based beamforming for wireless communicationCU24175AI-driven real-time beamforming optimization for 5G/MIMO networks, reducing latency, power use, and computational load.TagsArtificial intelligenceAutomationBeamformingInventorsJeremy JohnstonShixun WuXiaodong WangManagerGreg MaskelDepartmentsElectrical EngineeringDivisionsFu Foundation School of Engineering and Applied Science (SEAS)Release Date2025-06-26
Efficient and scalable bio-integrated AI system using brain organoidsCU24020Bio-integrated AI uses brain organoids and CMOS interfaces for scalable, energy-efficient reservoir computing with enhanced AI performance.TagsArtificial intelligenceAutonomous system (Internet)Brain mappingInventorsKenneth KosikKenneth ShepardManagerGreg MaskelDepartmentsElectrical EngineeringNeuroscienceDivisionsFu Foundation School of Engineering and Applied Science (SEAS)Release Date2024-05-27
Optical catheters and methods for diagnosis of uterine cancer and fibroidsCU23142An optical catheter using infrared and OCT spectrometry enables noninvasive, real-time differentiation of uterine cancer and fibroids.TagsCarcinomaCatheterCurettageInventorsAidan TherienArielle JoasilChristine P. HendonManagerDovina QuDepartmentsElectrical EngineeringDivisionsFu Foundation School of Engineering and Applied Science (SEAS)Release Date2024-01-18CollectionsOncologyMedical DeviceWomen's Health
Advanced computing RAM for enhanced artificial intelligence applicationsCU22064New SRAM-based in-memory AI accelerator boosts neural network speed and resilience, reducing energy use and system variability.TagsArtificial intelligenceComputerComputer memoryInventorsChuan-Tung LinDewei WangMingoo SeokManagerGreg MaskelDepartmentsElectrical EngineeringDivisionsFu Foundation School of Engineering and Applied Science (SEAS)Release Date2023-09-25
Method to Enhance Optical Coherence Tomography (OCT) for Eye Disease DetectionCU22266AI-enhanced portable OCT improves image quality and automatically detects AMD, enabling low-cost, accessible eye disease screening.TagsInternal medicineMacular degenerationNatural disasterInventorsChristine P. HendonDesmond YaoDonald Charles HoodManagerDovina QuDepartmentsElectrical EngineeringBiomedical EngineeringOphthalmologyDivisionsColumbia University Medical Center (CUMC)Faculty of the Arts & SciencesFu Foundation School of Engineering and Applied Science (SEAS)Release Date2023-02-20CollectionsOphthalmologyMedical DeviceDigital Health (Software, AI, bioinformatics, etc)
Algorithm for optimal bidding of energy storage into energy marketsCU22303Dynamic, fast algorithm optimizes energy storage bids in volatile markets to maximize operator profits and adapt to demand.TagsAlgorithmEnergy storageNonlinear systemInventorsBolun XuJoshua JaworskiNik ZhengManagerDovina QuDepartmentsElectrical EngineeringEarth & Environmental EngineeringDivisionsFu Foundation School of Engineering and Applied Science (SEAS)Release Date2022-08-20
Increased wireless throughput via an IF-filterless dual-conversion receiverCU20076IF-filterless dual-conversion receiver boosts wireless throughput, improving 5G compatibility with blocker tolerance and spurious rejection.TagsActive noise controlModulationInventorsGuoxiang HanPeter KingetTanbir HaqueManagerGreg MaskelDepartmentsElectrical EngineeringDivisionsFu Foundation School of Engineering and Applied Science (SEAS)Release Date2021-02-26
Miniaturized multi-clamp CMOS amplifier for intracellular electrophysiology recordingCU19222Ultra-compact CMOS multi-clamp intracellular amplifier enabling high-SNR voltage/current recordings with low power.TagsAmplifierBrainCMOSInventorsKenneth ShepardKrishna JayantSiddharth ShekarManagerGreg MaskelDepartmentsElectrical EngineeringDivisionsFu Foundation School of Engineering and Applied Science (SEAS)Release Date2020-07-21CollectionsCNS/Neurology
Composite material for biocompatible soft electronicsCU20070Biocompatible composite adhesive enabling high-resolution, non-invasive soft electronics for precise neural and bio-signal interfacing.TagsAnisotropyBiocompatibilityBiomaterialInventorsDion KhodagholyPatricia Jastrzebska-PerfectManagerDovina QuDepartmentsElectrical EngineeringDivisionsFu Foundation School of Engineering and Applied Science (SEAS)Release Date2020-04-16
Smart signaling of data through IP tunneling pathsProxy13Non-header signaling over IP tunnels enables QoS prioritization, reducing overhead and improving end-to-end session management.TagsComputer scienceConnected spaceInternetInventorsHenning SchulzrinneJongho Bang Ph.D.Qi Charles ShenManagerGreg MaskelDepartmentsElectrical EngineeringComputer ScienceDivisionsFu Foundation School of Engineering and Applied Science (SEAS)Release Date2018-10-20
Distributed differential oscillators for global clock networksM06-029Distributed differential oscillator network enables low-skew, low-jitter, low-power global clock distribution for high-frequency microprocessors.TagsAmplitudeClock signalDifferential signalingInventorsKenneth ShepardSteven ChanManagerGreg MaskelDepartmentsElectrical EngineeringDivisionsFu Foundation School of Engineering and Applied Science (SEAS)Release Date2018-10-20
Implantable ultrasound-powered microchipsCU15073Ultrasound-powered micron-scale IC chips wirelessly power and transmit real-time physiological data, enabling battery-free implants.TagsDrug deliveryElectric batteryElectrical energyInventorsChen ShiHongki KangJordan ThimotManagerGreg MaskelDepartmentsElectrical EngineeringDivisionsFu Foundation School of Engineering and Applied Science (SEAS)Release Date2018-04-07
Optically-powered micron-scale chip for electrophysiological measurements and intracellular probesCU16181An optically powered, sub-10 micron CMOS chip for injectable electrophysiology and intracellular sensing via light-driven power and data.TagsBiologyCMOSElectrophysiologyInventorsGirish RamakrishnanKenneth ShepardManagerGreg MaskelDepartmentsElectrical EngineeringDivisionsFu Foundation School of Engineering and Applied Science (SEAS)Release Date2018-02-27
RF receiver with tunable self-interference cancellation for high-quality FDD and SC-FD applicationsCU15077A compact RF receiver with tunable, wide-band self-interference cancellation enables high-quality FDD/SC-FD in a single IC.Tags65 nm processAttenuationBand-pass filterInventorsHarish KrishnaswamyJin ZhouManagerGreg MaskelDepartmentsElectrical EngineeringDivisionsFu Foundation School of Engineering and Applied Science (SEAS)Release Date2015-09-23
Permission-Based Sending (PBS) protocol for communication network security and traffic controlM09-001PBS enables permission-based sending to throttle traffic, prevent DoS, and enhance security with distributed, scalable on-path signaling.TagsAuthenticationCredit cardDNS root zoneInventorsHenning SchulzrinneSe Gi HongManagerGreg MaskelDepartmentsElectrical EngineeringComputer ScienceDivisionsFu Foundation School of Engineering and Applied Science (SEAS)Release Date2014-05-22
Error Free Analog to Digital ConversionM02-057Time-encoding converts analog signals to asynchronous time cues for low-voltage, error-free A/D and D/A conversion.TagsAmplitudeAnalog signalBinary numberInventorsAurel LazarLaszlo TothManagerGreg MaskelDepartmentsElectrical EngineeringDivisionsFu Foundation School of Engineering and Applied Science (SEAS)Release Date2002-04-30
Targeting the formation of aggressive cancer-associated fibroblasts for metastasis inhibition in solid tumorsCU21079Computationally maps adipose-derived cells transforming into COL11A1+ aCAFs to block metastasis across solid tumors.TagsAdipocyteAdipose tissueCancer immunotherapyInventorsDimitris AnastassiouKaiyi ZhuLingyi CaiManagerJerry KokoshkaDepartmentsElectrical EngineeringDivisionsFu Foundation School of Engineering and Applied Science (SEAS)Release Date2020-09-23CollectionsOncology
Deep learning method for improved anomaly detectionCU24165A deep learning framework using actor-critic and quantile regression to enhance anomaly detection with fewer labels and better thresholds.TagsAnomaly detectionComputer securityMachine learningInventorsXiaodong WangXiaoyang LiuZhenyan HuangManagerGreg MaskelDepartmentsElectrical EngineeringDivisionsFu Foundation School of Engineering and Applied Science (SEAS)Release Date2025-10-23
MOSbius: Custom integrated circuit for hands-on circuit design educationCU25175Custom CMOS IC + PCB lets students prototyping real transistor-level circuits on a breadboard, bridging simulation and lab practice.TagsBreadboardCMOSDebuggingInventorsPeter KingetManagerGreg MaskelDepartmentsElectrical EngineeringDivisionsFu Foundation School of Engineering and Applied Science (SEAS)Release Date2025-03-07
Trainable template search algorithm for efficient signal processingCU24045Trainable, low-dimensional template optimization rapidly detects signals in noisy, high-dimensional data with scalable, unrolled optimization.TagsAlgorithmComputer visionGradient descentInventorsJingkai YanJohn N. WrightShiyu WangManagerGreg MaskelDepartmentsElectrical EngineeringComputer SciencePhysicsDivisionsFaculty of the Arts & SciencesFu Foundation School of Engineering and Applied Science (SEAS)Release Date2024-08-23
Deep learning method for efficient energy storage arbitrageCU23109Deep-learning arbitrage predicts opportunity-value functions for robust, low-data, low-compute energy storage profit optimization.TagsAlgorithmArbitrageDeep learningInventorsBolun XuYousuf BakerManagerDovina QuDepartmentsElectrical EngineeringEarth & Environmental EngineeringDivisionsFu Foundation School of Engineering and Applied Science (SEAS)Release Date2023-01-30
Compact, Ultra-Low-Power Time-Delay Estimation Circuit for Sound LocalizationCU18288Ultra-low-power PCC-ATDE time-delay circuit for 3D sound localization, enabling always-on, miniaturized, energy-efficient sensing.TagsAnalog-to-digital converterCross-correlationElectric batteryInventorsDaniel de Godoy PeixotoPeter KingetXiaofan "Fred" JiangManagerGreg MaskelDepartmentsElectrical EngineeringDivisionsFu Foundation School of Engineering and Applied Science (SEAS)Release Date2019-03-15
Chip-scale photonics platform with integrated wavelength-tunable laserCU16333Chip-scale photonics with integrated tunable laser enables low-power, broadband, narrow-linewidth steering for sensing, quantum, AR, LiDAR.TagsEndoscopyNumerical apertureOptogeneticsInventorsAseema MohantyFelippe BarbosaMichal LipsonManagerGreg MaskelDepartmentsElectrical EngineeringDivisionsFu Foundation School of Engineering and Applied Science (SEAS)Release Date2018-02-27
Machine learning-guided software for the ablation of cardiac arrhythmiasCU22127Machine-learning software analyzes electroanatomic data to automatically identify arrhythmia isthmuses, speeding and simplifying ablation.TagsAlgorithmCardiac muscleCatheterInventorsAmardeep SalujaChristine P. HendonZiyi HuangManagerDovina QuDepartmentsElectrical EngineeringMedicineDivisionsColumbia University Medical Center (CUMC)Fu Foundation School of Engineering and Applied Science (SEAS)Release Date2024-05-27
Wireless implantable device for optical brain imaging in freely moving animalsCU19385Wireless implantable, fully wireless optical brain imaging probe enables high-resolution, optogenetic interrogation in freely moving animals.TagsAction potentialBrain mappingCMOSInventorsEric PollmannKenneth ShepardSajjad MoazeniManagerGreg MaskelDepartmentsElectrical EngineeringDivisionsFu Foundation School of Engineering and Applied Science (SEAS)Release Date2020-07-21CollectionsCNS/Neurology
Optical spectroscopy enabled three-dimensional substrate mappingCU19293Near-infrared 3D epicardial mapping distinguishes scar from fat, guiding VT ablation with lipid content-aware imaging.TagsAdipose tissueCardiac muscleCatheterInventorsChristine P. HendonJames McLeanRajinder Singh-MoonManagerDovina QuDepartmentsElectrical EngineeringDivisionsFu Foundation School of Engineering and Applied Science (SEAS)Release Date2020-04-17
Photonic multiplexing and demultiplexing between free space and on-chip technologiesCU17068Photonic link between free space and on-chip devices streams, splits, and analyzes wavelengths with modular polymer waveguides.TagsLaserMultiplexingOptical communicationInventorsMichal LipsonMohammad Amin TadayonManagerGreg MaskelDepartmentsElectrical EngineeringDivisionsFu Foundation School of Engineering and Applied Science (SEAS)Release Date2020-02-14
Flexible implantable probe for large-scale wireless neural stimulation and recordingCU15023A flexible, wireless, battery-free CMOS neural probe enabling large-scale, high-density brain stimulation and recording with minimal tissue disturbance.TagsBrainCMOSElectrophysiologyInventorsDavid TsaiHongki KangKenneth ShepardManagerGreg MaskelDepartmentsElectrical EngineeringDivisionsFu Foundation School of Engineering and Applied Science (SEAS)Release Date2018-04-07
A compact, alias-free, and energy-efficient analog-to-digital converter for integrated electronicsCU14248Clockless, alias-free ADC with low power, compact area, and tunable resolution for sensors, imaging, and high-frequency DSP.TagsAliasingAmplitudeAnalog signalInventorsSharvil Pradeep PatilYannis TsividisManagerGreg MaskelDepartmentsElectrical EngineeringDivisionsFu Foundation School of Engineering and Applied Science (SEAS)Release Date2016-03-11
Sub-harmonic spatio-temporal conductance modulation for non-reciprocal circuitsCU16298Magnetic-free, sub-harmonic clock enables tunable non-reciprocity in circulators/isolators for RF–THz integrated circuits.TagsCMOSData compressionExtremely high frequencyInventorsHarish KrishnaswamyTolga DincManagerGreg MaskelDepartmentsElectrical EngineeringDivisionsFu Foundation School of Engineering and Applied Science (SEAS)Release Date2018-02-27
Energy-efficient continuous-time digital signal processing systemCU16130Energy-efficient CT-DSP with event-driven feedback reduces power and hardware, boosting continuous-time signal processing.TagsDiscrete time and continuous timeFeedbackFrequency responseInventorsYannis TsividisYu ChenManagerGreg MaskelDepartmentsElectrical EngineeringDivisionsFu Foundation School of Engineering and Applied Science (SEAS)Release Date2018-02-27
Passive low noise amplifier achieves linear signal amplification and complete noise cancellation for high performance integrated circuit applicationsCU14031Passive three-coil, fully passive LNA delivers linear gain with complete noise cancellation, enabling ultra-low-voltage, high-performance receivers.TagsActive noise controlBluetoothCMOSInventorsBaradwaj VigrahamPeter KingetManagerGreg MaskelDepartmentsElectrical EngineeringDivisionsFu Foundation School of Engineering and Applied Science (SEAS)Release Date2014-10-07
