Tags
Drug delivery
View all technologies
Parameters to maximize nebulized
drug
delivery
to larynx
CU24050
Patient-specific CT-based nebulization parameters optimize aerosol size and velocity to maximize laryngeal drug deposition.
Tags
Drug delivery
Aerosol
Hypersensitivity
Inventors
Michael Pitman MD
Manager
Cynthia Lang
Departments
Otolaryngology
Divisions
Columbia University Medical Center (CUMC)
Release Date
2024-07-05
Multi-lumen microneedle for intracochlear
drug
delivery
and sampling
CU21117
Ultra-sharp multi-lumen microneedles enable simultaneous intracochlear drug delivery and perilymph sampling with zero net volume change.
Tags
Drug delivery
Cochlea
Diffusion
Inventors
Anil Lalwani
Aykut Aksit
Jeffrey W. Kysar
Manager
Dovina Qu
Departments
Mechanical Engineering
Otolaryngology
Divisions
Columbia University Medical Center (CUMC)
Fu Foundation School of Engineering and Applied Science (SEAS)
Release Date
2024-09-26
Ultrasound-responsive microcapsules for localized and on-demand
drug
delivery
CU22072
Ultrasound-triggered, biphasic microcapsules enable on-demand, localized drug release with reduced systemic toxicity and long-term payload stability.
Tags
Drug delivery
Chemotherapy
Dextran
Inventors
Margaret Jakus
Rachel D. Field
Samuel Sia Ph.D.
Manager
Dovina Qu
Departments
Biomedical Engineering
Divisions
Fu Foundation School of Engineering and Applied Science (SEAS)
Release Date
2023-07-20
Microneedle array for cross-barrier
drug
delivery
in the eye, ear and central nervous system
CU18171
Biodegradable microneedle arrays enable precise, cross-barrier drug delivery to the eye, ear, and CNS with controlled release.
Tags
Drug delivery
3D printing
Biodegradation
Inventors
Anil Lalwani
Aykut Aksit
Daniel N. Arteaga
Manager
Dovina Qu
Departments
Mechanical Engineering
Otolaryngology
Divisions
Columbia University Medical Center (CUMC)
Fu Foundation School of Engineering and Applied Science (SEAS)
Release Date
2023-01-24
Injectable hydrogels for therapeutic
delivery
CU25086
Injectable, biocompatible hydrogels crosslinked by extracellular vesicles for bioactive, scalable regenerative therapy delivery.
Tags
Drug delivery
Biocompatibility
Biomaterial
Inventors
Artemis Margaronis
Caterina Piunti
Cindy Huilin Lu
Manager
Dovina Qu
Departments
Biomedical Engineering
Divisions
Fu Foundation School of Engineering and Applied Science (SEAS)
Release Date
2025-07-15
Convection-enhanced
delivery
of topotecan and dexamethasone for malignant gliomas
CU25031
Implantable pump enables chronic, targeted brain delivery of topotecan plus dexamethasone via convection-enhanced delivery for glioma.
Tags
Drug delivery
Adjuvant therapy
Animal disease model
Inventors
Jeffrey Bruce
Peter Canoll
Manager
Jerry Kokoshka
Departments
Neurological Surgery
Pathology & Cell Biology
Divisions
Columbia University Medical Center (CUMC)
Release Date
2025-08-29
Inhalation device for targeted therapeutic
delivery
to the throat
CU23297
A portable, disposable inhaler delivering nebulized natural therapeutics to the larynx with precise 10–35 micron particles.
Tags
Drug delivery
Disposable product
Hoarse voice
Inventors
Michael Pitman MD
Manager
Cynthia Lang
Departments
Otolaryngology
Divisions
Columbia University Medical Center (CUMC)
Release Date
2024-07-05
Collagen wrap for ligament repair
CU25026
Collagen wrap shields ACL wounds from negative synovial factors while enabling nutrient diffusion and targeted drug delivery for healing.
Tags
Drug delivery
Anterior cruciate ligament
Collagen
Inventors
Andy J. Lee
Clark Hung
Gerard Agop Ateshian
Manager
Dovina Qu
Departments
Biomedical Engineering
Divisions
Fu Foundation School of Engineering and Applied Science (SEAS)
Release Date
2025-11-12
Modified exosomes for enhanced cargo
delivery
CU21165
ATP-loaded exosomes boost cellular uptake of cargo by delivering energy currencies (ATP/NADH) for enhanced therapeutic delivery.
Tags
Drug delivery
Biocompatibility
Endocytosis
Inventors
Akiva Mintz
Fatemeh Momen-Heravi
Manager
Joan Martinez
Departments
College of Dental Medicine
Radiology
Divisions
Columbia University Medical Center (CUMC)
Release Date
2023-08-24
In vivo internalizing RGD peptide production for enhanced treatment of solid tumors
CU25033
In vivo iRGD plasmid drives tumor penetration, reducing immunosuppression; co-administers with CAR-T/ therapies for enhanced efficacy.
Tags
Drug delivery
Angiogenesis
Cancer immunotherapy
Inventors
Kazuki N. Sugahara
Norio Miyamura
Manager
Jerry Kokoshka
Departments
Surgery
Divisions
Columbia University Medical Center (CUMC)
Release Date
2025-11-20
Blood-brain barrier opening and cavitation imaging using a single diagnostic imaging array
CU21007
Single diagnostic ultrasound array opens the blood-brain barrier and images cavitation simultaneously for cost-effective, targeted brain therapy.
Tags
Drug delivery
Beamforming
Blood–brain barrier
Inventors
Elisa Konofagou
Mark T. Burgess
Robin Ji
Manager
Dovina Qu
Departments
Biomedical Engineering
Divisions
Fu Foundation School of Engineering and Applied Science (SEAS)
Release Date
2025-07-29
Coherent factor-based passive cavitation mapping for monitoring of focused ultrasound treatment
CU22079
Coherent factor-based passive acoustic mapping enables real-time, high-resolution, low-cost monitoring of transcranial focused ultrasound treatment.
Tags
Drug delivery
Ablation
Acoustics
Inventors
Elisa Konofagou
Sua Bae
Manager
Dovina Qu
Departments
Biomedical Engineering
Divisions
Fu Foundation School of Engineering and Applied Science (SEAS)
Release Date
2025-11-07
Focused ultrasound nanoparticles for targeted imaging and neuroregeneration
CU21224
Ultrasound-activated nanocup theranostics cross BBB for targeted Alzheimer’s imaging and neuroregenerative therapy.
Tags
Drug delivery
Amyloid beta
Antibody
Inventors
Antonios Poulipoulos
Elisa Konofagou
Manager
Dovina Qu
Departments
Biomedical Engineering
Divisions
Fu Foundation School of Engineering and Applied Science (SEAS)
Release Date
2025-07-29
Nanoparticle-functionalized scaffolds for biomedical applications
CU24234
Electrospun, nanoparticle-functionalized scaffolds deliver immunomodulatory cues for enhanced wound healing and tissue regeneration.
Tags
Drug delivery
Agonist
Antibody
Inventors
Jose McFaline-Figueroa
Santiago Correa
Treena Arinzeh
Manager
Dovina Qu
Departments
Biomedical Engineering
Divisions
Fu Foundation School of Engineering and Applied Science (SEAS)
Release Date
2025-02-16
Programmable nanoencapsulation for probiotic
delivery
CU21284
Programmable nanoencapsulated probiotics boost cancer therapy safety and efficacy by tunable, immune-evasive bacterial delivery.
Tags
Drug delivery
Bacteria
Bacterial capsule
Inventors
Jaeseung Hahn
Kam Leong
Tal Danino
Manager
Cynthia Lang
Departments
Biomedical Engineering
Divisions
Fu Foundation School of Engineering and Applied Science (SEAS)
Release Date
2023-01-30
Collections
Oncology
Microneedle for eye injection surgery
CU24034
Minimally invasive ophthalmic microneedle enables precise subretinal/intravascular injections, improving retinal safety and targeting.
Tags
Drug delivery
Artery
Birth defect
Inventors
Ahmet Hondur
Anil Lalwani
Aykut Aksit
Manager
Dovina Qu
Departments
Mechanical Engineering
Ophthalmology
Otolaryngology
Divisions
Columbia University Medical Center (CUMC)
Fu Foundation School of Engineering and Applied Science (SEAS)
Release Date
2024-12-12
Photocatalysis method with low-energy light
CU18169
Photon upconversion enables infrared-driven, safer photocatalysis with deeper penetration for pharma, biomedicine, and materials.
Tags
Drug delivery
Antimicrobial
Biomedicine
Inventors
Andrew B. Pun
Benjamin Ravetz
Daniel N. Congreve
Manager
Greg Maskel
Departments
Chemistry
Divisions
Faculty of the Arts & Sciences
Massachusetts Eye and Ear Infirmary
Release Date
2024-12-06
Self-assembling DNA polymer scaffolds with material templates
CU24073
3D DNA frameworks templated with metals/semiconductors enable advanced nanolithography and multifunctional nanoscale material integration.
Tags
Drug delivery
Crystal structure
Inorganic compound
Inventors
Oleg Gang
Manager
Greg Maskel
Departments
Chemical Engineering/Applied Chemistry
Divisions
Fu Foundation School of Engineering and Applied Science (SEAS)
Release Date
2024-12-06
Microneedle-endoscope for drugging and sampling of inner ear
CU21365
A camera-guided microneedle endoscope perforates the round window to deliver drugs and sample inner ear fluids safely.
Tags
Drug delivery
3D printing
Inventors
Anil Lalwani
Aykut Aksit
Jeffrey W. Kysar
Manager
Dovina Qu
Departments
Mechanical Engineering
Otolaryngology
Divisions
Columbia University Medical Center (CUMC)
Fu Foundation School of Engineering and Applied Science (SEAS)
Release Date
2024-07-18
Endogenous pro-fertility capsids
CU23365
Endogenous capsid-like delivery targets subfertility non-invasively, enabling hormone-independent pro-fertility treatment for both sexes.
Tags
Drug delivery
Assisted reproductive technology
Capsid
Inventors
Harrison Cullen
Luke E. Berchowitz PhD
Thomas Wood
Manager
Jerry Kokoshka
Departments
Genetics & Development
Divisions
Columbia University Medical Center (CUMC)
Release Date
2024-07-09
Nanofibrous scaffold for controlled release of small molecule immunomodulators
CU24040
Nanofibrous scaffold locally releases ACHP to inhibit NF-kB, enabling targeted immunomodulation with reduced systemic effects.
Tags
Drug delivery
Autoimmune disease
Biomaterial
Inventors
Fereshteh Zandkarimi
Hannah Childs
Helen Lu Ph.D.
Manager
Joan Martinez
Departments
Biological Sciences
Biomedical Engineering
Divisions
Faculty of the Arts & Sciences
Fu Foundation School of Engineering and Applied Science (SEAS)
Release Date
2023-12-18
Collections
Small Molecule
A deep learning substitute for Gadolinium contrast detects focused ultrasound-induced blood-brain barrier (BBB) opening
CU23205
AI predicts focused ultrasound BBB openings from low-dose GBCA MRI, reducing gadolinium exposure and scan time.
Tags
Drug delivery
Blood–brain barrier
Central nervous system
Inventors
Andrew F. Laine
Cheng-Chia Wu
Jia Guo
Manager
Jerry Kokoshka
Departments
Biomedical Engineering
Psychiatry
Radiation Oncology
Divisions
Columbia University Medical Center (CUMC)
Fu Foundation School of Engineering and Applied Science (SEAS)
Release Date
2023-11-30
Collections
CNS/Neurology
Platform/Research Tool
Medical Device
Probiotic scaffolds for COPD prevention and treatment
CU23062
Probiotic-infused electrospun scaffolds deliver targeted oral therapy to prevent COPD progression by combating respiratory pathogens.
Tags
Drug delivery
Adjuvant
Bronchodilator
Inventors
Aaron J. Moment
Helen Lu Ph.D.
Ming Chau Chan
Manager
Joan Martinez
Departments
Biomedical Engineering
Chemical Engineering/Applied Chemistry
Divisions
Fu Foundation School of Engineering and Applied Science (SEAS)
Release Date
2023-05-02
γ-secretase complex inhibitor nanoparticles for NASH
CU20227
Liver-targeted γ-secretase inhibitor nanoparticles reverse NASH fibrosis, reducing Notch-associated toxicity and enabling liver-specific therapy.
Tags
Drug delivery
Atherosclerosis
Dyslipidemia
Inventors
Li Qiang
Utpal Pajvani
Zhen Gu
Manager
Cynthia Lang
Departments
Medicine
Pathology and Cell Biology
Divisions
Columbia University Medical Center (CUMC)
Naomi Berrie Diabetes Center
Release Date
2023-01-31
Conversion and condition-resistant regulatory T-cells for immunosuppressive therapy and tissue repair
CU22040
CRISPR-edited, CAR Tregs with enhanced stability resist conversion and antibody depletion, boosting immunosuppression and transplant tolerance.
Tags
Drug delivery
Autoimmune disease
Chimeric antigen receptor T cell
Inventors
Megan Sykes M.D.
Mohsen Khosravi Maharlooei
Remi Creusot
Manager
Jerry Kokoshka
Departments
Medicine
Divisions
Columbia University Medical Center (CUMC)
Release Date
2023-01-30
Collections
Oncology
Scalable, high-throughput
drug
delivery
platform using cell-membrane coating technology for nanoparticles
CU20253
Rapid, scalable membrane-coated nanoparticle production via flash nanocomplexation enables uniform biomimetic drug/gene delivery carriers.
Tags
Drug delivery
Biomaterial
Biomimetics
Inventors
Hanze Hu
Kam Leong
Manager
Dovina Qu
Departments
Biomedical Engineering
Divisions
Fu Foundation School of Engineering and Applied Science (SEAS)
Release Date
2020-07-16
Collections
Platform/Research Tool
Myopia treatment and prevention using S-methyl-L-Thiocitrulline and its derivatives
CU20384
Inhibits neuronal NO synthase with S-methyl-L-thiocitrulline derivatives to prevent and treat myopia, via oral/topical delivery.
Tags
Drug delivery
Contact lens
Enzyme inhibitor
Inventors
Andrei Tkatchenko
Tatiana V. Tkatchenko
Manager
Kristin Neuman
Departments
Ophthalmology
Divisions
Columbia University Medical Center (CUMC)
Release Date
2022-10-08
Collections
Ophthalmology
Small Molecule
High-pressure injector device for comfortable and rapid
drug
delivery
CU18187
High-pressure, spring-free injector enables rapid, quiet delivery of viscous drugs for self-administration and higher concentration dosing.
Tags
Drug delivery
Adrenaline
Biopharmaceutical
Inventors
Ozgur Sahin
Manager
Dovina Qu
Departments
Biological Sciences
Divisions
Faculty of the Arts & Sciences
Release Date
2019-12-03
Compounds for treating myopia
CU20379
A library of eye-development–targeting compounds treats or prevents myopia via versatile administration with minimal side effects.
Tags
Drug delivery
Atropine
Combination therapy
Inventors
Andrei Tkatchenko
Tatiana V. Tkatchenko
Manager
Kristin Neuman
Departments
Ophthalmology
Divisions
Columbia University Medical Center (CUMC)
Release Date
2022-10-08
Collections
Ophthalmology
Small Molecule
Intra-arterial administration of peptide-
drug
conjugates for tumor-selective
drug
delivery
CU17144
Intra-arterial, flow-arrest delivery preserves cationic peptide-drug charge, enhancing tumor and brain tumor targeting.
Tags
Drug delivery
Apoptosis
Blood–brain barrier
Inventors
Shailendra Joshi
Manager
Sara Gusik
Departments
Anesthesiology
Release Date
2019-08-21
Serotonin targeting in the gut to treat anxiety and depression
CU21281
Gut-targeted serotonin modulation offers safer, pregnancy-safe mood disorder treatment with fewer systemic side effects.
Tags
Drug delivery
Attention deficit hyperactivity disorder
Breastfeeding
Inventors
Kam Leong
Kara Margolis
Mark Ansorge
Manager
Dovina Qu
Departments
Biomedical Engineering
Pediatrics
Psychiatry
Divisions
College of Physicians and Surgeons (CUMC
Columbia University Medical Center (CUMC)
Fu Foundation School of Engineering and Applied Science (SEAS)
Release Date
2021-04-16
Collections
CNS/Neurology
Women's Health
Cell-penetrating TAT oligomers for
drug
delivery
CU17314
Cell-penetrating TAT oligomers enable targeted drug delivery across membranes, including blood-brain barriers, for tumors and CNS.
Tags
Drug delivery
Apoptosis
Biopharmaceutical
Inventors
Shailendra Joshi
Manager
Sara Gusik
Departments
Anesthesiology
Release Date
2018-07-16
Collections
Oncology
Structure-stabilized DNA origami-based
drug
and gene
delivery
CU20002
Peptoid-coated DNA origami stabilizes nanocarriers for drug/gene delivery under physiological conditions, enabling targeted, protected therapeutics.
Tags
Drug delivery
Biomaterial
Buffer solution
Inventors
Carolyn Bertozzi
Oleg Gang
Ronald Zuckerman
Manager
Greg Maskel
Departments
Chemical Engineering/Applied Chemistry
Sponsored Projects Office
Divisions
Fu Foundation School of Engineering and Applied Science (SEAS)
LBNL
Release Date
2019-07-01
Wearable engineered human skin that can be generated in curved, custom shapes
CU20263
Wearable, curved-skin grafts: custom-shaped, vascularized human skin for improved grafting, disease modeling, and drug screening.
Tags
Drug delivery
Autotransplantation
Biophysical environment
Inventors
Hasan Erbil Abaci
Manager
Dovina Qu
Departments
Dermatology
Divisions
Columbia University Medical Center (CUMC)
Release Date
2020-02-18
Collections
Platform/Research Tool
Medical Device
Stem cell-based gene
delivery
for biological pacemakers
1352
Biological pacemaker using engineered human mesenchymal stem cells to autonomously regulate heart rhythm without batteries.
Tags
Drug delivery
Artificial cardiac pacemaker
Cardiac muscle cell
Inventors
Ira S. Cohen
Michael Rosen M.D.
Peter Brink
Manager
Jerry Kokoshka
Departments
Anesthesiology
Pharmacology
Physiology and Cellular Biophysics
Divisions
Columbia University Medical Center (CUMC)
Release Date
2018-11-30
Cyclopropenium polymer particles for improved gene
delivery
CU15012
Cyclopropenium polymer particles enable non-viral, pH-stable, modular, low-toxicity gene/drug delivery with targeted loading.
Tags
Drug delivery
Antimicrobial
Biomolecule
Inventors
Jessica L. Freyer
Kathryn Louise Killops
Luis Campos
Manager
Cynthia Lang
Departments
Chemistry
Divisions
Faculty of the Arts & Sciences
Release Date
2018-04-02
Non-viral gene
delivery
agents
CU16329
Non-viral, cyclopropenium-based polymer transfection agents enable stable, low-toxicity DNA delivery across cell membranes.
Tags
Drug delivery
Carbon
Gene expression
Inventors
Jessica L. Freyer
Luis Campos
Spencer Daniel Brucks
Manager
Cynthia Lang
Departments
Chemistry
Divisions
Faculty of the Arts & Sciences
Release Date
2018-02-23
Wearable ultrasound device for targeted mapping and modulation of brain tissue
CU15312
Wearable focused ultrasound maps and modulates brain tissue, temporarily opening the BBB for noninvasive, localized neuromodulation and drug delivery.
Tags
Drug delivery
Blood–brain barrier
Brain
Inventors
Elisa Konofagou
Gesthimani Samiotaki
Manager
Dovina Qu
Departments
Biomedical Engineering
Radiology
Divisions
Columbia University Medical Center (CUMC)
Fu Foundation School of Engineering and Applied Science (SEAS)
Release Date
2018-04-13
Implantable ultrasound-powered microchips
CU15073
Ultrasound-powered micron-scale IC chips wirelessly power and transmit real-time physiological data, enabling battery-free implants.
Tags
Drug delivery
Electric battery
Electrical energy
Inventors
Chen Shi
Hongki Kang
Jordan Thimot
Manager
Greg Maskel
Departments
Electrical Engineering
Divisions
Fu Foundation School of Engineering and Applied Science (SEAS)
Release Date
2018-04-07
Improved security architecture for cyber-physical systems using rebooting and diversification
CU16331
YOLO CPS security: periodic micro-reboots with program diversification to curb attacks, using inertia to preserve operation.
Tags
Drug delivery
Computer security
Industrial control system
Inventors
Jonathan Weisz
Lakshminarasimhan Sethumadhavan
Miguel A. Arroyo
Manager
Greg Maskel
Departments
Computer Science
Divisions
Fu Foundation School of Engineering and Applied Science (SEAS)
Release Date
2018-03-09
Remotely-activated implantable device for targeted
drug
delivery
CU12228
Biocompatible hydrogel iMEMS delivers targeted, externally triggered doxorubicin release (HIFU preferred) with deep tissue access.
Tags
Drug delivery
3D printing
Biocompatibility
Inventors
Olga Ordeig
Samuel Sia
Manager
Dovina Qu
Departments
Biomedical Engineering
Divisions
Fu Foundation School of Engineering and Applied Science (SEAS)
Release Date
2016-04-04
Microbubbles for blood oxygenation and
drug
delivery
2420
Microbubble-based oxygen delivery and targeted drug transport offer rapid, portable, customizable emergency and research applications.
Tags
Drug delivery
Acute respiratory distress syndrome
Anticonvulsant
Inventors
Francis X. McGowan
John Kheir
Mark Andrew Borden
Manager
Dovina Qu
Departments
Anesthesiology, Perioperative and Pain Medicine
Chemical Engineering/Applied Chemistry
Divisions
Anesthesiology
Division of Critical Care MedicineDepartment of Anesthesiology,Perioperative a
Fu Foundation School of Engineering and Applied Science (SEAS)
Release Date
2016-03-02
Targeted, thermo-responsive
drug
delivery
for treating cancer
CU15296
Thermo-responsive, biodegradable polymer-drug conjugate enables targeted, heat-triggered cancer delivery with low toxicity and tunable release.
Tags
Drug delivery
Biodegradation
Hyperthermia
Inventors
Chathuranga De Silva
Jeffrey Thomas Koberstein
Sanjoy Samanta
Manager
Dovina Qu
Departments
Chemical Engineering/Applied Chemistry
Divisions
Fu Foundation School of Engineering and Applied Science (SEAS)
Release Date
2015-10-30
Thermo-responsive, biodegradable polymers for targeted
drug
delivery
CU14314
Thermo-responsive, biodegradable polymers enable targeted, pH-triggered drug delivery with tunable LCST and non-toxic degradation.
Tags
Drug delivery
Biodegradation
Chemical synthesis
Inventors
Jeffrey Thomas Koberstein
Sanjoy Samanta
Manager
Dovina Qu
Departments
Chemical Engineering/Applied Chemistry
Divisions
Fu Foundation School of Engineering and Applied Science (SEAS)
Release Date
2015-03-28
Core-centered, porous ceramic granules employ bio-agent
delivery
system for enhanced bone repair/regeneration
CU13158
Core-centered porous ceramic granules with micro-pores and drug-delivery microspheres enhance bone repair and infection prevention.
Tags
Drug delivery
Antibiotic
Biodegradation
Inventors
Daniel Sunho Oh
Departments
Orthopedic Surgery
Divisions
Columbia University Medical Center (CUMC)
Release Date
2015-11-10
Focused ultrasound protocol for
drug
delivery
2781
Focused ultrasound with optimized short pulse sequences opens the blood-brain barrier for targeted, non-invasive brain drug delivery.
Tags
Drug delivery
Blood–brain barrier
Brain
Inventors
Elisa Konofagou
James Junesik J. Choi
Manager
Dovina Qu
Departments
Biomedical Engineering
Divisions
Fu Foundation School of Engineering and Applied Science (SEAS)
Release Date
2014-09-15
Specific inhibition of caspase-2 activation for the treatment of neurodegenerative diseases
CU12019
Membrane-penetrable hexapeptide selectively blocks caspase-2-RAIDD, halting neuron death for neurodegenerative therapies.
Tags
Drug delivery
Amyotrophic lateral sclerosis
Caspase
Inventors
Carol M. Troy MD, PhD
Manager
Jerry Kokoshka
Departments
Pathology
Divisions
Columbia University Medical Center (CUMC)
Release Date
2015-12-09
Low-tech, minimally invasive localized brain
drug
delivery
system
CU14052
Portable, MRI-free, single-transducer brain BBB opening using intermediate-frequency ultrasound for targeted, low-tech drug delivery.
Tags
Drug delivery
Blood–brain barrier
Cavitation
Inventors
Elisa Konofagou
Fabrice Marquet
Tobias Teichert
Manager
Dovina Qu
Departments
Biomedical Engineering
Biomedical Informatics
Neuroscience
Divisions
Columbia University Medical Center (CUMC)
Fu Foundation School of Engineering and Applied Science (SEAS)
Release Date
2014-08-25
Targeted
drug
delivery
with focused ultrasound induced blood-brain barrier opening
CU14035
Acoustically activated nanodroplets enable focused ultrasound–mediated blood-brain barrier opening for targeted brain drug delivery.
Tags
Drug delivery
Acoustics
Blood vessel
Inventors
Chen Chen
Elisa Konofagou
Manager
Dovina Qu
Departments
Biomedical Engineering
Divisions
Fu Foundation School of Engineering and Applied Science (SEAS)
Release Date
2014-09-16
Focused ultrasound system for localized
drug
delivery
across the blood brain barrier
2039
Focused ultrasound with microbubbles locally and reversibly opens the BBB, enabling targeted brain drug delivery and CNS research.
Tags
Drug delivery
Aperture
Blood–brain barrier
Inventors
Elisa Konofagou
James Junesik J. Choi
Mathieu Pernot
Manager
Dovina Qu
Departments
Biomedical Engineering
Neurology
Divisions
Columbia University Medical Center (CUMC)
Fu Foundation School of Engineering and Applied Science (SEAS)
Release Date
2014-09-15