PDFgetE v3.0: Next-generation pair distribution functions extraction from electron diffraction dataCU20203Next-gen ePDF tool extracts total scattering pair distribution functions from standard electron microscopes for nanoscale structure. TagsAmorphous solidCouplingElectron diffractionInventorsSimon Billinge Ph.D.ManagerGreg MaskelDepartmentsApplied Physics & Applied MathDivisionsFu Foundation School of Engineering and Applied Science (SEAS)Release Date2020-03-05
Clinical application of Electromechanical Wave Imaging (EWI) to localize arrhythmiasCU25148Non-invasive arrhythmia source localization using EWI on standard ultrasound scanners, enabling clinical mapping without high-framerate data.TagsArrhythmiaCardiac muscleEchocardiographyInventorsElisa KonofagouMelina TourniManagerDovina QuDepartmentsBiomedical EngineeringDivisionsFu Foundation School of Engineering and Applied Science (SEAS)Release Date2026-01-16
CRISPR-modified microorganisms for rare-earth element recoveryCU22215CRISPR-Cas12a engineering of Acidithiobacillus ferrooxidans to boost iron oxidation and rare-earth biomining in acidic environments.TagsAssayBacteriaCRISPRInventorsHeejung JungScott A. BantaYuta InabaManagerDovina QuDepartmentsChemical Engineering/Applied ChemistryDivisionsFu Foundation School of Engineering and Applied Science (SEAS)Release Date2025-12-17
Humanoid-robot capable of facial co-expressionCU24301A soft-skinned humanoid robot predicts and synchronizes facial expressions in real time, enhancing natural human-robot interaction.TagsAnimatronicsAnthropomorphismAugmented realityInventorsHod LipsonYuhang HuManagerDovina QuDepartmentsMechanical EngineeringDivisionsFu Foundation School of Engineering and Applied Science (SEAS)Release Date2025-02-03
Self-assembling DNA polymer scaffolds with material templatesCU240733D DNA frameworks templated with metals/semiconductors enable advanced nanolithography and multifunctional nanoscale material integration.TagsCrystal structureDrug deliveryInorganic compoundInventorsOleg GangManagerGreg MaskelDepartmentsChemical Engineering/Applied ChemistryDivisionsFu Foundation School of Engineering and Applied Science (SEAS)Release Date2024-12-06
Dephasing optimization through coherence order pathway selection (DOTCOPS) for improved crusher and phase cycling schemes in MR spectroscopyCU18146DOTCOPS automates optimal crusher and phase-cycle schemes in MR spectroscopy, suppressing unwanted coherence pathways across sequences.TagsAlgorithmMagnetic fieldMagnetic resonance imagingInventorsChristoph JuchemKarl LandheerManagerJoan MartinezDepartmentsBiomedical EngineeringDivisionsFu Foundation School of Engineering and Applied Science (SEAS)Release Date2024-09-18CollectionsMedical DeviceDigital Health (Software, AI, bioinformatics, etc)
Compact optical generation of ultra-low-noise microwave signalsCU22190Compact, chip-scale optical oscillators deliver ultra-low-noise microwave signals with built-in noise suppression and no active electronics.TagsAnalogue electronicsData communicationHard disk driveInventorsAlexander GaetaBok Young KimJae JangManagerGreg MaskelDepartmentsApplied Physics & Applied Math (APAM)Electrical EngineeringDivisionsFu Foundation School of Engineering and Applied Science (SEAS)Release Date2026-02-27
Non-invasive laser therapy for cytokine modulation and corneal inflammation managementCU18315Femtosecond laser therapy non-invasively modulates corneal cytokines to reduce inflammation and keratocyte apoptosis, preserving tissue.TagsAnalgesicAntibioticApoptosisInventorsSinisa VukelicManagerDovina QuDepartmentsMechanical EngineeringDivisionsFu Foundation School of Engineering and Applied Science (SEAS)Release Date2024-08-17CollectionsOphthalmology
Nucleic acid biosensor system for point-of-care diagnosticsCU20204A CRISPR-transposase nucleic acid biosensor enables rapid, sensitive, point-of-care detection of RNA and DNA pathogens.TagsAcidAdenoviridaeBiosafetyInventorsHarris WangKenneth ShepardSamuel H. SternbergManagerCynthia LangDepartmentsBiochemistry & Molecular BiophysicsBiomedical EngineeringElectrical EngineeringDivisionsFu Foundation School of Engineering and Applied Science (SEAS)Columbia University Medical Center (CUMC)Release Date2026-06-26
Hardware architecture for implantable brain-computer interface system-on-chipCU25171Implantable brain-chip architecture executes ML models on-device, enabling real-time neural processing, reducing data transmission and overhead.TagsArtificial intelligenceAssistive technologyBrain–computer interfaceInventorsGuy EichlerLuca CarloniManagerGreg MaskelDepartmentsComputer ScienceDivisionsFu Foundation School of Engineering and Applied Science (SEAS)Release Date2026-01-16
Super-resolution microscopy using tunable fluorescent nanodiamondsCU12035Deterministic emitter switch microscopy with tunable fluorescent nanodiamonds enables rapid, 12–15 nm super-resolution imaging and sensing.TagsCharge-coupled deviceConfocal microscopyDiffraction-limited systemInventorsDirk EnglundManagerGreg MaskelDepartmentsElectrical EngineeringDivisionsFu Foundation School of Engineering and Applied Science (SEAS)Release Date2017-04-21
AI-assisted C-to-Rust translation for safer legacy software modernizationCU26072Automates scalable C-to-Rust migration with safety-focused refinement, reducing unsafe code while preserving behavior and tests.TagsLegacy systemParallel computingPointer (computer programming)InventorsBaishakhi RayManagerGreg MaskelDepartmentsComputer ScienceDivisionsFu Foundation School of Engineering and Applied Science (SEAS)Release Date2026-07-17
Reconfigurable AI accelerator for power-constrained edge devicesCU26320Reconfigurable Field-programmable Systolic-Array accelerates AI on power-limited edge devices with efficient, adaptable FPGA-based compute.TagsConsumer electronicsEdge computingField-programmable gate arrayInventorsBiruk SeyoumLuca CarloniManagerGreg MaskelDepartmentsComputer ScienceDivisionsFu Foundation School of Engineering and Applied Science (SEAS)Release Date2026-07-06
Ultra-compact, low-loss and high-speed optical phase shifter for high-speed modulationCU21328Ultra-compact 2D-material optical phase shifter enables low-power, high-speed (15 GHz) modulation in silicon nitride photonics.TagsAmplitude modulationCapacitorChalcogenideInventorsIpshita DattaJames HoneMichal LipsonManagerGreg MaskelDepartmentsElectrical EngineeringMechanical EngineeringDivisionsFu Foundation School of Engineering and Applied Science (SEAS)Fu Foundation School of Engineering andRelease Date2026-07-06
Biopolymer-stabilized clay for 3D printingCU26250Biopolymer-stabilized clay enhances 3D-printed earthen materials, boosting strength, buildability, and low-carbon construction.Tags3D printingBiopolymerCarbon footprintInventorsMaierdan YierfanRachel Lola Ben-AlonShiho KawashimaManagerDovina QuDepartmentsCivil Engineering and Engineering MechanicsGraduate School of Architecture, Planning and PreservationDivisionsFu Foundation School of Engineering and Applied Science (SEAS)Graduate School of Architecture, Planning and Preservation (GSAPP)Release Date2026-04-20
tomoLIBRA: Deep learning software for automated volumetric breast density estimationCU26015AI-based tomoLIBRA estimates volumetric breast density from standard 3D DBT images, enabling scalable, retrospective risk assessment without raw data.TagsBreast cancerBreast cancer screeningCase–control studyInventorsAimilia GastouniotiAri BrooksCeline VachonManagerJoan MartinezDepartmentsBiomedical EngineeringRadiologyDivisionsFu Foundation School of Engineering and Applied Science (SEAS)Columbia University Medical Center (CUMC)School of MedicineRelease Date2026-02-20CollectionsArtificial Intelligence (AI)
Infrared photonic crystal spectrometerM11-035A compact, robust, no-moving-parts infrared spectrometer using photonic crystal arrays for 2D wavelength resolution.TagsCryogenicsFourier-transform infrared spectroscopyInfrared spectroscopyInventorsJohn Ioannis KymissisMarshall CoxNadia PervezManagerGreg MaskelDepartmentsApplied Physics & Applied Math (APAM)Electrical EngineeringDivisionsFu Foundation School of Engineering and Applied Science (SEAS)Release Date2026-02-14
Encryption method for secure storage and analysis of patient data on the cloudCU24094A cloud-friendly, privacy-preserving genomic analysis method using homomorphic encryption to enable multi-user queries on encrypted patient data.TagsCiphertextCloud computingData managementInventorsGamze GursoyJacob BlindenbachJiayi KangManagerJoan MartinezDepartmentsBiomedical InformaticsComputer ScienceDivisionsFu Foundation School of Engineering and Applied Science (SEAS)Columbia University Medical Center (CUMC)Release Date2026-02-03
Configurable Kalman filtering for brain-computer interfacesCU25167Configurable, energy-efficient Kalman filtering enables real-time, low-power neural decoding for embedded brain-computer interfaces.TagsAlgorithmData communicationElectrodeInventorsGuy EichlerJoseph ZuckermanLuca CarloniManagerGreg MaskelDepartmentsComputer ScienceDivisionsFu Foundation School of Engineering and Applied Science (SEAS)Release Date2026-01-16
Stepwise process for the sustainable recovery of rare metals and earth elementsCU21163Recovery of gold and rare earths from electronic waste via a green, stepwise supercritical CO2 and antisolvent process. 132 charactersTagsAcidCalciumCopperInventorsAh-Hyung Alissa ParkHaonan Danny HuangPeng PengManagerDovina QuDepartmentsEarth & Environmental EngineeringDivisionsFu Foundation School of Engineering and Applied Science (SEAS)Release Date2025-10-30
Virtual reality platform for upper limb motor rehabilitationCU25025VR platform for unconstrained upper-limb rehabilitation, enabling natural-movement tasks to improve motor function and real-world readiness.TagsMotor controlNeuronVirtual realityInventorsRobert CarreraSunil K. AgrawalManagerDovina QuDepartmentsBiomedical EngineeringMechanical EngineeringDivisionsFu Foundation School of Engineering and Applied Science (SEAS)Release Date2025-07-29
Real-time generation of radiology reports using generative AICU25102Real-time AI-generated radiology reports accelerate turnaround, ensure interpretability, translation to 120 languages, and PHI redaction.TagsComputer visionHuman errorRadiologyInventorsAli DadgarShahab JalalvandManagerGreg MaskelDepartmentsMechanical EngineeringDivisionsFu Foundation School of Engineering and Applied Science (SEAS)Release Date2025-06-02CollectionsArtificial Intelligence (AI)
xPDFsuite - an end-to end software solution for atomic pair distribution function analysisM11-120End-to-end Python-based PDF analysis suite enabling rapid, batch-friendly total scattering characterization of amorphous, nanocrystalline materials.TagsAmorphous solidBatch processingEnergyInventorsChris FarrowPavol JuhasSimon Billinge Ph.D.ManagerGreg MaskelDepartmentsApplied Physics & Applied Math (APAM)DivisionsFu Foundation School of Engineering and Applied Science (SEAS)Release Date2025-03-03
Environmentally friendly conversion of carbon dioxide into carbon nanofibersCU24182Electrochemical-thermochemical CO2-to-CNF conversion at ambient conditions using FeCo catalyst; earns greener, scalable carbon nanofiber production.TagsAlloyCarbonCarbon dioxideInventorsJingguang ChenSamay GargZhenhua XieManagerGreg MaskelDepartmentsChemical Engineering/Applied ChemistryDivisionsFu Foundation School of Engineering and Applied Science (SEAS)Release Date2025-01-30
Compact, low power beam steering platforms for optical scanning and projection displaysCU18261Compact, low-power chip-scale beam steering platform enabling near-IR to visible optical routing, scanning, and projection.TagsAluminium oxideInfraredLaserInventorsAseema MohantyMichal LipsonOscar Adrian Jimenez GordilloManagerGreg MaskelDepartmentsElectrical EngineeringDivisionsFu Foundation School of Engineering and Applied Science (SEAS)Release Date2025-01-17
Scalable software and hardware for deep neural network developmentCU24101Log-normal weight initialization and constrained training for scalable, resource-efficient deep neural networks across architectures.TagsComputer visionDeep learningFacial recognition systemInventorsManasi Gurunath KhandekarN. SanjeevrajanVenkat VenkatasubramanianManagerGreg MaskelDepartmentsChemical Engineering/Applied ChemistryElectrical EngineeringDivisionsFu Foundation School of Engineering and Applied Science (SEAS)Release Date2024-10-25CollectionsArtificial Intelligence (AI)
Metasurface Holographic Optical Traps for Ultracold AtomsCU24064Metasurface holographic traps enable compact, scalable, high-precision ultracold-atom control for quantum computing and simulation.TagsAcousticsAmplitudeDielectricInventorsNanfang YuSebastian Will Ph.D.ManagerGreg MaskelDepartmentsApplied Physics & Applied MathPhysicsDivisionsFu Foundation School of Engineering and Applied Science (SEAS)Faculty of the Arts & SciencesRelease Date2024-05-27
Selective laser treatment of carbon fiber compositesCU23313Programmable laser curing creates flexible CFRP structures with predesigned bends, enabling deployable, complex aerospace and defense components.TagsCarbon fibersLaserLaunch vehicleInventorsHayley McClintockHod LipsonManagerDovina QuDepartmentsMechanical EngineeringDivisionsFu Foundation School of Engineering and Applied Science (SEAS)Release Date2024-05-27
Small scale screening bioreactor with airway tissues and mucosa for the progression and treatment of lung diseaseCU23307Bioreactor recreating mucus-lined airways ex vivo for real-time, high-throughput modeling and therapeutic screening.TagsBiomimeticsBioreactorCell cultureInventorsGordana Vunjak-NovakovicJinho KimKeith YeagerManagerCynthia LangDepartmentsBiomedical EngineeringDivisionsFu Foundation School of Engineering and Applied Science (SEAS)Release Date2024-04-08
Hybrid multi-coil technique for improving magnetic resonance imaging (MRI)CU23207Hybrid, compact multi-coil and RF magnet system enhances MRI field homogeneity, boosting clinical brain imaging on standard machines.TagsHuman brainMagnetic fieldMagnetic resonance imagingInventorsCarlotta IannielloChristoph JuchemSebastian TheilenbergManagerJoan MartinezDepartmentsBiomedical EngineeringDivisionsFu Foundation School of Engineering and Applied Science (SEAS)Release Date2024-03-26CollectionsCNS/NeurologyMedical Device
Enhanced CMOS amplifier nanopore sensor for ion channel analysisCU12278Enhanced CMOS nanopore amplifier boosts high-throughput, high-resolution ion channel sensing for drug discovery and diagnostics. (136 characters)TagsAmplifierCMOSDNA sequencingInventorsJacob RosensteinKenneth ShepardSiddharth Ramakrishnan PhDManagerGreg MaskelDepartmentsElectrical EngineeringDivisionsFu Foundation School of Engineering and Applied Science (SEAS)Release Date2023-11-21
Rapid monitoring of community heath through wastewater surveillanceCU23120Wastewater surveillance for SARS-CoV-2 enables high-throughput community viral load, variant detection, and outbreak prediction.TagsAcidBioinformaticsDNA sequencingInventorsKartik ChandranManagerDovina QuDepartmentsEarth & Environmental EngineeringDivisionsFu Foundation School of Engineering and Applied Science (SEAS)Release Date2023-04-15CollectionsDigital Health (Software, AI, bioinformatics, etc)
Computer vision enabled immersive audio for blind and low-vision sports fansCU23071Sensor-free, 3D spatialized audio over real-time tennis video via computer vision, aiding blind/low-vision fans.TagsBadmintonComputer visionTennisInventorsBasel HindiBrian Anthony SmithConnor CourtienManagerGreg MaskelDepartmentsComputer ScienceDivisionsFu Foundation School of Engineering and Applied Science (SEAS)Release Date2023-01-17CollectionsArtificial Intelligence (AI)
COWS: Water suppression algorithm for magnetic resonance spectroscopyCU21111Flexible COWS water suppression for MRSI, customizable pulses/durations, shorter experiments, improved macromolecule visualization.TagsAlgorithmMacromoleculeNuclear magnetic resonance spectroscopyInventorsChristoph JuchemKarl LandheerMartin GajdosikManagerJoan MartinezDepartmentsBiomedical EngineeringDivisionsFu Foundation School of Engineering and Applied Science (SEAS)Release Date2020-11-13CollectionsDigital Health (Software, AI, bioinformatics, etc)
Multi-material inverted selective laser sintering 3D printerCU19152Inverted SLS 3D printer enables multi-material parts with controllable strength/porosity and reduced waste.Tags3D printingLaserPorosityInventorsHod LipsonJohn WhiteheadManagerDovina QuDepartmentsMechanical EngineeringDivisionsFu Foundation School of Engineering and Applied Science (SEAS)Release Date2019-11-21
System for monitoring the smart grid management of electric transmission and distribution systemsM10-068A machine-learning system continuously evaluates capital, maintenance, and operations of smart grids to predict failures and optimize investments.TagsEfficient energy useElectrical gridMachine learningInventorsAlbert G. BoulangerLeon Li WuRoger N. AndersonManagerDovina QuDepartmentsCenter for Computational Learning Systems (CCLS)CS/SEASCS/SEAS and LDEO/EIDivisionsFu Foundation School of Engineering and Applied Science (SEAS)Release Date2018-08-30
Thermostable microring modulators for use in optical devicesCU14094Thermostable silicon microring modulators with mean-power feedback stabilize resonance, enabling compact, low-power, high-speed optical links.TagsEnergyIntegrated circuitLaserInventorsAndrew KnightsDylan LoganKeren BergmanManagerGreg MaskelDepartmentsElectrical EngineeringDivisionsFu Foundation School of Engineering and Applied Science (SEAS)Fu Foundation School of Engineering andRelease Date2018-04-13
Maximizing solar harvest with minimal sensor algorithm for adaptive solar panel positioningCU26090Minimal-sensing solar panel orientation uses four photodetectors and scale-space math to maximize light capture in varied indoor/outdoor lighting.TagsActuatorAlgorithmConsumer electronicsInventorsJeremy KlotzShree Kumar NayarManagerGreg MaskelDepartmentsComputer ScienceDivisionsFu Foundation School of Engineering and Applied Science (SEAS)Release Date2026-06-26
Method to identifying drug targets from single-cell perturbation screensCU25189Integrated single-cell CRISPR perturbations and drug screens with Bayesian deconvolution to identify and rank drug targets.TagsDNA barcodingDeconvolutionDrug developmentInventorsDavid A. Knowles Ph.D.Isabella N. GrabskiRahul SatijaManagerJoan MartinezDepartmentsComputer ScienceDivisionsFu Foundation School of Engineering and Applied Science (SEAS)Release Date2026-06-24
Engineered bacterial platform for localized cancer therapyCU26042Engineered bacteria deliver localized chemoimmunotherapy to tumors, combining prodrug activation, IL-15 boosting, and PD-L1 blockade.TagsBacteriaBiopharmaceuticalChemotherapyInventorsJongwon ImNicholas ArpaiaTal DaninoManagerCynthia LangDepartmentsBiomedical EngineeringMicrobiologyDivisionsFu Foundation School of Engineering and Applied Science (SEAS)Columbia University Medical Center (CUMC)Release Date2026-05-15
Porous electrolytic cell for acid and base productionCU26056Membrane-free electrolytic cell efficiently produces acid and base from brine; low-cost, impurity-tolerant, tunable pH. 15 words, ~129 charactersTagsAcidBrineChloralkali processInventorsDaniel Vincent EspositoLauren GreenleeManagerDovina QuDepartmentsChemical Engineering/Applied ChemistryDivisionsFu Foundation School of Engineering and Applied Science (SEAS)Release Date2026-05-01
Durable bacterial cellulose biotextiles for sustainable applicationsCU20202Durable, non-toxic bacterial cellulose biotextiles with enzyme tanning offer water/flame resistance for sustainable, scalable fabrics.TagsAldehydeBacteriaBiodegradationInventorsAdrian ChituChristian JosephHelen LuManagerDovina QuDepartmentsBiomedical EngineeringCenter for Integrated Science & Engineering (CISE)Materials ScienceDivisionsFu Foundation School of Engineering and Applied Science (SEAS)FAS & SEASRelease Date2026-05-01
Patient-specific computational model for cardiovascular surgery planningCU25246Patient-specific virtual-surgery algorithm predicts post-op hemodynamics to guide optimal congenital heart surgery decisions.TagsAlgorithmCardiac surgeryCongenital heart defectInventorsDavid KalfaVijay VedulaYurui ChenManagerKristin NeumanDepartmentsMechanical EngineeringSurgeryDivisionsFu Foundation School of Engineering and Applied Science (SEAS)Columbia University Medical Center (CUMC)Release Date2026-03-06
Surgical imaging device for minimally invasive surgery2381An insertable, stereoscopic surgical imaging device enabling single-port, fully internal visualization with pan-tilt-zoom and lighting.TagsDepth perceptionLaparoscopyLensInventorsDennis FowlerPeter AllenManagerKristin NeumanDepartmentsComputer ScienceSurgeryDivisionsFu Foundation School of Engineering and Applied Science (SEAS)Columbia University Medical Center (CUMC)Release Date2026-03-06
Robotic system for accelerated motor skills acquisition in sportsCU25023Robotic assist-as-needed sports training blends motion capture and pelvic/torso force guidance to accelerate motor skill learning.TagsArtificial intelligenceBiomedical engineeringElectroencephalographyInventorsSunil K. AgrawalManagerDovina QuDepartmentsMechanical EngineeringDivisionsFu Foundation School of Engineering and Applied Science (SEAS)Release Date2026-02-14
Humidity-responsive textiles for adaptive moisture managementCU22375Humidity-responsive textiles dynamically adjust breathability via reversible hygromorphing, passively regulating moisture and comfort without power.TagsElastic modulusHumidityLipid bilayerInventorsOzgur SahinYocheved UngarManagerDovina QuDepartmentsApplied Physics & Applied Math (APAM)Biological SciencesDivisionsFu Foundation School of Engineering and Applied Science (SEAS)Faculty of the Arts & SciencesRelease Date2026-02-14
Adaptive machine learning platform for image-based rapid diagnostic test interpretationCU21034Adaptive AI interprets diverse rapid tests from images with self-supervised pretraining, smartphone-ready and scalable.TagsArtificial neural networkMachine learningQuality controlInventorsDavid ColburnGuangxing HanJiawei MaManagerDovina QuDepartmentsBiomedical EngineeringComputer ScienceElectrical EngineeringDivisionsFu Foundation School of Engineering and Applied Science (SEAS)Release Date2026-02-14CollectionsArtificial Intelligence (AI)
Nanoscale plug-enabled membranes for efficient hydrogen productionCU25218Electrochemical nanoscale plugs seal membrane pinholes, cutting hydrogen crossover dramatically while preserving proton conductivity.TagsAcidElectrochemistryElectrolysis of waterInventorsAlan WestDaniel Vincent EspositoJesse DondapatiManagerDovina QuDepartmentsChemical Engineering/Applied ChemistryDivisionsFu Foundation School of Engineering and Applied Science (SEAS)Release Date2026-01-16
Attention-based framework for cell-cell communication analysisCU26099Dynamic, attention-based AMICI framework reveals time-varying cell-cell interactions and signaling nodes in tissue contexts.TagsAttention (machine learning)Cell signalingDevelopmental biologyInventorsElham AziziJustin HongKhushi DesaiManagerJoan MartinezDepartmentsBiomedical EngineeringComputer ScienceDivisionsFu Foundation School of Engineering and Applied Science (SEAS)Release Date2025-12-04CollectionsArtificial Intelligence (AI)
Brain-informed speech separation (BISS) for auditory speech signal enhancementCU21093Brain-informed speech separation (BISS) uses neural signals and deep learning to isolate and enhance target speech in noisy environments.TagsActive noise controlElectroencephalographyHearing lossInventorsEnea CeoliniNima MesgaraniManagerKristin NeumanDepartmentsElectrical EngineeringMortimer B. Zuckerman Mind Brain Behavior InstituteDivisionsFu Foundation School of Engineering and Applied Science (SEAS)Release Date2025-11-20CollectionsArtificial Intelligence (AI)